Results 171 to 180 of about 1,415,876 (303)

PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines

FEBS Open Bio, EarlyView.
Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart, Manon Van den Abbeel, Christoph Schifflers, Karim Bouhjar, Andrea Scarmelotto, Alexis Khelfi, Anne‐Catherine Wera, Carine Michiels   +7 more
wiley   +1 more source

When Heat Meets Pollutants: Integrating Degree-Days and Chemical Activity Concepts for the Assessment of Temperature-Driven Toxicity. [PDF]

Environ Sci Technol
Gorokhova E, Alurralde G, Steigerwald S, Abel S, Saladin Y, Sobek A, Eriksson-Wiklund AK, Garbaras A.   +7 more
europepmc   +1 more source

Generic calibration of a simple model of diurnal temperature variations for spatial analysis of accumulated degree-days. [PDF]

Int J Biometeorol, 2018
Felber R, Stoeckli S, Calanca P.
europepmc   +1 more source

Identification of functional murine mitochondrial formyl peptides and their effects on myeloid‐derived suppressor cell generation

FEBS Open Bio, EarlyView.
We first identified functional murine mitochondrial N‐formyl peptides (MT‐FPs) and investigated their effects on the in vitro myeloid‐derived suppressor cell (MDSC) generation from bone marrow cells. We demonstrated that MT‐FPs acted directly on bone marrow cells to promote MDSC generation and modulated the polymorphonuclear (PMN)‐MDSC/monocyte (M ...
Miyako Ozawa, Saori Kagoshima, Akira Yamada   +2 more
wiley   +1 more source

Predicting the Onset Date of Cucumber Powdery Mildew Based on Growing Degree Days and Leaf Wetness Duration in Greenhouse Environment. [PDF]

Plant Pathol J
Son M, Jeong H, Jung JY, Park J, Park J, Park H, Yoon J, Jung SH, Sim CB, Kim KH, Park SY.   +10 more
europepmc   +1 more source

Variability of growing degree days in Poland in response to ongoing climate changes in Europe. [PDF]

Int J Biometeorol, 2017
Wypych A, Sulikowska A, Ustrnul Z, Czekierda D.   +3 more
europepmc   +1 more source

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

FEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui, Taobo Hu, Thomson Christian Husein, Wai Hei Shek, Bingrong Chen, Depeng Wang, Shu Wang, Weichuan Yu, Xiaodan Fan, Mengping Long, Toyotaka Ishibashi   +10 more
wiley   +1 more source

Exploring Fasciola infection dynamics in Coastal Caspian Sea region: implications of growing degree days (GDD) and Malone index across varied climatic zones in Iran. [PDF]

Parasitol Res
Meshgi B, Modabbernia G, Meshgi K.
europepmc   +1 more source

U.S. Agro-Climate in 20^th Century: Growing Degree Days, First and Last Frost, Growing Season Length, and Impacts on Crop Yields. [PDF]

Sci Rep, 2018
Kukal MS, Irmak S.
europepmc   +1 more source

Quantitative proteomic analysis reveals different characteristics of bladder cancer cells after exposure to bisphenol A

FEBS Open Bio, EarlyView.
Bisphenol A (BPA), a common chemical in plastics, exerts dual effects on bladder cancer cells: low doses promote growth and migration, while high doses suppress growth and migration. Multi‐omics and bioinformatics reveal BPA acts via MAPK and inflammatory pathways.
Shaomin Niu, Lanlan Li, Wenjuan Jia, Hanzhong Feng, Xiaoquan Yu, Youli Zhao, Fengzhi Yuan, Hui Ding, Junqiang Tian, Yong‐Xing He, Zhiping Wang   +10 more
wiley   +1 more source