Results 141 to 150 of about 48,154 (256)

Decreased degree centrality values as a potential neuroimaging biomarker for migraine: A resting-state functional magnetic resonance imaging study and support vector machine analysis. [PDF]

Front Neurol, 2022
Wang Q, Gao Y, Zhang Y, Wang X, Li X, Lin H, Xiong L, Huang C.   +7 more
europepmc   +1 more source

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

Molecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak, Iva Staniczková Zambo, Matěj Přikryl, Peter Múdry, Danica Zapletalová, Jarmila Navrátilová, Jiří Navrátil, Jan Šmarda, Liudmyla Drobot, Petr Beneš, Lucia Knopfová   +10 more
wiley   +1 more source

Fatigue, monocyte activation, and degree centrality of the thalamus in post-menopausal women living with HIV. [PDF]

Brain Imaging Behav
Dillon K, Lobo J, Pallikkuth S, Levin B, McIntosh R.   +4 more
europepmc   +1 more source

Shared and Unique Effects of Long-Term Administration of Methylphenidate and Atomoxetine on Degree Centrality in Medication-Naïve Children With Attention-Deficit/Hyperactive Disorder. [PDF]

Int J Neuropsychopharmacol, 2022
Fu Z, Yuan J, Pei X, Zhang K, Xu C, Hu N, Xie R, Zhao Y, Wang Y, Yang L, Cao Q.   +10 more
europepmc   +1 more source

Revisiting Mission‐Oriented Cancer Research to tackle the increasing burden of cancer in Europe–a policy perspective

Molecular Oncology, EarlyView.
Translational cancer research and its implementation through competitively selected Comprehensive Cancer Centers across Europe should be the primary policy focus for addressing the increasing cancer burden in Europe and counteract the present main strategy to convert cancer to a chronic disease.
Manuel Heitor, Julio Celis, Ulrik Ringborg   +2 more
wiley   +1 more source

Abnormal Intrinsic Functional Hubs in Corneal Ulcer: Evidence from a Voxel-Wise Degree Centrality Analysis. [PDF]

J Clin Med, 2022
Chen MJ, Huang R, Liang RB, Pan YC, Shu HY, Liao XL, Xu SH, Ying P, Kang M, Zhang LJ, Ge QM, Shao Y.   +11 more
europepmc   +1 more source

Checkpoint blockade and the stem‐like T cell trade‐off

Molecular Oncology, EarlyView.
Stem‐like T cells are key to the success of programmed cell death protein 1 (PD1) blockade, as they sustain long‐term anti‐tumor response by continuously generating effector CD8+ T cells. However, how these cells are maintained in cancer is not fully understood. Hor et al.
Julie M. Mazet, Johanna A. Joyce
wiley   +1 more source

Impaired degree centrality and effective connectivity contributed to deficits in cognition and depression in patients with temporal lobe epilepsy. [PDF]

Sci Rep
Qin B, Su S, Chen X, Sun Y, Zhou Q, Hu H, Qin L, Zheng J.   +7 more
europepmc   +1 more source

The Degree Centrality and Functional Connectivity in Patients With Temporal Lobe Epilepsy Presenting as Ictal Panic: A Resting State fMRI Study. [PDF]

Front Neurol, 2022
Chang W, Liu J, Nie L, Pang X, Lv Z, Zheng J.   +5 more
europepmc   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source