Results 131 to 140 of about 16,346,212 (324)

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Constructing ecological interaction networks by correlation analysis: hints from community sampling [PDF]

open access: yesNetwork Biology, 2011
A set of methodology for constructing ecological interaction networks by correlation analysis of community sampling data was presented in this study. Nearly 30 data sets at different levels of taxa for different sampling seasons and locations were used ...
WenJun Zhang
doaj  

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

Research on unequal error protection of irregular LDPC codes

open access: yesTongxin xuebao, 2005
An irregular low-density parity-check (LDPC) code with unequal error protection (UEP) property was proposed. A weight-increasing parity-check (WIPC) matrix was constructed.
MA Pi-ming, YUAN Dong-feng, YANG Xiu-mei
doaj  

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Assortative mixing in spatially-extended networks

open access: yesScientific Reports, 2018
We focus on spatially-extended networks during their transition from short-range connectivities to a scale-free structure expressed by heavy-tailed degree-distribution.
Vladimir V. Makarov   +7 more
doaj   +1 more source

Limit distributions of maximum vertex degree in a conditional configuration graph

open access: yesTransactions of the Karelian Research Centre of the Russian Academy of Sciences, 2018
We consider configuration graphs with N vertices. The degrees of the vertices are independent identically distributed  random variables following the power-law distribution with positive parameter τ.
Irina Cheplyukova
doaj   +1 more source

Clusters’ size-degree distribution for bond percolation [PDF]

open access: yesPhysica A: Statistical Mechanics and its Applications, 2018
To address some physical properties of percolating systems it can be useful to know the degree distributions in finite clusters along with their size distribution. Here we show that to achieve this aim for classical bond percolation one can use the $q \to 1$ limit of suitably modified q-state Potts model.
openaire   +3 more sources

PICALM::MLLT10 translocated leukemia

open access: yesFEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen   +7 more
wiley   +1 more source

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