Results 131 to 140 of about 16,346,212 (324)
The newfound relationship between extrachromosomal DNAs and excised signal circles
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Constructing ecological interaction networks by correlation analysis: hints from community sampling [PDF]
A set of methodology for constructing ecological interaction networks by correlation analysis of community sampling data was presented in this study. Nearly 30 data sets at different levels of taxa for different sampling seasons and locations were used ...
WenJun Zhang
doaj
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
Research on unequal error protection of irregular LDPC codes
An irregular low-density parity-check (LDPC) code with unequal error protection (UEP) property was proposed. A weight-increasing parity-check (WIPC) matrix was constructed.
MA Pi-ming, YUAN Dong-feng, YANG Xiu-mei
doaj
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Assortative mixing in spatially-extended networks
We focus on spatially-extended networks during their transition from short-range connectivities to a scale-free structure expressed by heavy-tailed degree-distribution.
Vladimir V. Makarov +7 more
doaj +1 more source
Limit distributions of maximum vertex degree in a conditional configuration graph
We consider configuration graphs with N vertices. The degrees of the vertices are independent identically distributed random variables following the power-law distribution with positive parameter τ.
Irina Cheplyukova
doaj +1 more source
Clusters’ size-degree distribution for bond percolation [PDF]
To address some physical properties of percolating systems it can be useful to know the degree distributions in finite clusters along with their size distribution. Here we show that to achieve this aim for classical bond percolation one can use the $q \to 1$ limit of suitably modified q-state Potts model.
openaire +3 more sources
PICALM::MLLT10 translocated leukemia
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen +7 more
wiley +1 more source

