To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley +1 more source
A block matrix incremental feature selection method based on fuzzy rough minimum classification error. [PDF]
Chen Z, Xing M, Li J.
europepmc +1 more source
Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini +2 more
wiley +1 more source
Inf-sup stable space-time Local Discontinuous Galerkin method for the heat equation. [PDF]
Gómez S, Perinati C, Stocker P.
europepmc +1 more source
Interplay between RNA‐protein interactions and RNA structures in gene regulation
Methodological advances in mapping transcriptome‐wide RNA‐protein interactions and RNA structures have started to uncover the potential of RNP conformations in gene regulation. Competing RNA–RNA, RNA‐protein and protein–protein interactions shape the compaction and function of RNPs throughout their lifetime and may provide novel therapeutic targets in ...
Jenni Rapakko +2 more
wiley +1 more source
A fast, accurate and oscillation-free spectral collocation solver for high-dimensional transport problems. [PDF]
Cavallini N +3 more
europepmc +1 more source
Minimal degrees of unsolvability and the full approximation construction [PDF]
Richard L. Epstein
openalex +1 more source
A general model for analysis of linear and hyperbolic enzyme inhibition mechanisms
We developed a general enzyme kinetic model that integrates these six basic inhibition mechanism onto a single one. From this model, we deduced a general enzyme kinetic equation that through modulation of simple parameters, γ (the relative inhibitor affinity for two binding sites) and β (the reactivity of the enzyme–substrate–inhibitor complex), is ...
Rafael S. Chagas, Sandro R. Marana
wiley +1 more source
The Ground-Set-Cost Budgeted Maximum Coverage Problem. [PDF]
van Heuven van Staereling I +2 more
europepmc +1 more source
Capacity Approximations of Mimo Interference Channels: Beyond Degrees of Freedom
Yimin Pang
openalex +1 more source

