Results 71 to 80 of about 167,528,363 (247)

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Microstructure Evolution and Phase Stability of ODS Steel During Spark Plasma Sintering

Alloys
The effect of spark plasma sintering (SPS) temperature on the structural and phase state and the physicomechanical properties of an ODS steel based on the Fe-Cr-Y2O3 system was investigated.
Lyudmila Yerygina, Nuriya Mukhamedova, Arman Miniyazov, Igor Sokolov, Aisara Sabyrtayeva, Danil Kulbedin, Ospan Oken   +6 more
doaj   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source

Compressibility characteristics and coefficient of consolidation determination for unsaturated sand treated with micro silica

Scientific Reports
This study investigated the influence of Micro-Silica (MS) on the compressibility of poorly graded sand, with the aim of determining coefficient of consolidation ( $${c}_{v}$$ ).
Bestun J. Shwan
doaj   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source

Impact of the solid volume fraction of clay and consolidation on the erodibility of sand-mud mixtures

International Journal of Sediment Research
The erodibility of sediment mixtures is a key factor in sediment dynamic processes and morphological evolution in coastal environments. However, it remains insufficiently understood.
Zhonghao Zhao, Yuan Xu, Xianye Wang, Jianwei Sun, Qing He   +4 more
doaj   +1 more source

Study on the Calculation of the Post-construction Settlement after the Secondary Preloading of Sand Pile Composite Foundation of the High-speed Railway

MATEC Web of Conferences, 2018
To complete the technology upgrade of the Kunshan section of the Beijing-Shanghai Railway, the secondary preloading of the original sand pile foundation was carried out in five years after the completion of the railway.
Shen Zuo, Jin Li, Li Zhang
doaj   +1 more source

Case history and back-analysis of large-scale embankment construction on peat using vacuum consolidation [PDF]

E3S Web of Conferences
This presentation discusses engineering considerations for designing and constructing large-scale embankments on peat deposits in Hokkaido, northern Japan, using the vacuum consolidation method with Prefabricated Vertical Drains (PVDs).
Takahashi Hideaki, Shiraga Shinichiro, Sakakibara Tsukasa, Kochi Taishi, Nishimura Satoshi   +4 more
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Challenges of Bank Consolidation to the Central Bank of Nigeria: A Descriptive Analysis [PDF]

Consolidation is one of the trends that characterize banking industry restructuring in Nigeria. However, the emerging scale of bank mergers raises challenging policy questions that must be addressed by policy makers in the course of promoting economic ...
Ahmad Bello, Dogarawa
core