Results 31 to 40 of about 240,647 (250)

Comparative Evaluation of Hemodiafiltration, Hemoperfusion, and Standard Hemodialysis on Efficacy, Inflammatory Control, Dialysis Adequacy, and Safety in End‐Stage Renal Disease: A Prospective Observational Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo, Weisi Dai, Jie Mao, Mei Ye, Xingshan Lu, Xiaocui Zhang   +5 more
wiley   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

Wavefront Shaping with Varying Degrees of Freedom [PDF]

EPJ Web of Conferences
Optical wavefront shaping employs the linearity of scattering to focus light through scattering media using spatial modulation. By selectively switching off weakly-contributing segments, we significantly improve optimization speeds with minimal intensity
Hubert Maël, Mulder L. (Bert), Vreman Timon J., Tromp Tamara A. M., Lagendijk Ad, Vos Willem L.   +5 more
doaj   +1 more source

Longitudinal genome‐wide aneuploidy measurements in circulating cell‐free DNA to predict lack of benefit from pembrolizumab in patients with metastatic urothelial cancer

Molecular Oncology, EarlyView.
Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi, Stavros Makrodimitris, Sandra van Wilpe, Iris te Paske, Vanja de Weerd, Corine M. Beaufort, Hans M. Westgeest, Jens Voortman, Maureen J. B. Aarts, Maud Rijnders, Astrid A. M. van der Veldt, Ronald de Wit, Niven Mehra, Saskia M. Wilting, Debbie G. J. Robbrecht   +14 more
wiley   +1 more source

New dynamical degrees of freedom from invertible transformations

Journal of High Energy Physics, 2023
We show that invertible transformations of dynamical variables can change the number of dynamical degrees of freedom. Moreover, even in cases when the number of dynamical degrees of freedom remains unchanged, the resulting dynamics can be essentially ...
Pavel Jiroušek, Keigo Shimada, Alexander Vikman, Masahide Yamaguchi   +3 more
doaj   +1 more source

The crystal structure of the Borrelia burgdorferi nicotinamidase BBE22 resolves a long‐standing annotation error

FEBS Open Bio, EarlyView.
The crystal structure of Borrelia burgdorferi nicotinamidase (PncA/BBE22) reveals the correct full‐length protein initiated from a non‐canonical AUU start codon. The structure validates previous biochemical findings and resolves a long‐standing annotation error, demonstrating that the truncated database sequence is structurally incompatible with the ...
Kalvis Brangulis
wiley   +1 more source

Combining environment and task manipulation improves the development of individual creativity in futsal players

Frontiers in Sports and Active Living
IntroductionLiterature on the effect of task and environment manipulation with the purpose of stimulating creative actions in futsal is promising yet limited.
Behzad Mohammadi Orangi, Behrouz Ghorbanzadeh, Mansoureh Shahraki, Mozhgan Memarmoghaddam, Matthieu Lenoir   +4 more
doaj   +1 more source

Multiple Sclerosis Relapse Activity After Ozanimod Discontinuation in DAYBREAK Trial Participants

Annals of Clinical and Translational Neurology, EarlyView.
Multiple Sclerosis Relapse Activity After Ozanimod Discontinuation in DAYBREAK Trial Participants. ABSTRACT Objective Return of disease activity is expected when patients discontinue disease‐modifying therapy (DMT) for multiple sclerosis (MS). Some MS DMTs are associated with higher‐than‐expected disease activity (rebound) after discontinuation.
Ralf Gold, Krzysztof W. Selmaj, Regina Berkovich, Jeffrey A. Cohen, Giancarlo Comi, Eva K. Havrdová, James K. Sheffield, Hetal Desai, Chun‐Yen Cheng, Jon V. Riolo, Andrew Thorpe, Erik DeBoer, Bruce A. C. Cree   +12 more
wiley   +1 more source

A Pedagogic Exploration of Researcher Degrees of Freedom

Spreadsheets in Education, 2014
In this article, I present a spreadsheet that demonstrates how researcher degrees of freedom (RDoF) increase type 1 errors in scientific research. RDoF refer to the flexibility in analyzing and reporting data.
Christopher R Fisher
doaj  

Charm degrees of freedom in hot matter from lattice QCD

Physics Letters B
We study the nature of charm degrees of freedom in hot strong interaction matter by performing lattice QCD calculations of the second and fourth-order cumulants of charm fluctuations, and their correlations with net baryon number, electric charge and ...
A. Bazavov, D. Bollweg, O. Kaczmarek, F. Karsch, Swagato Mukherjee, P. Petreczky, C. Schmidt, Sipaz Sharma   +7 more
doaj   +1 more source