Results 91 to 100 of about 276,793 (321)

Dehydration affects drug transport over nasal mucosa

open access: yesDrug Delivery, 2019
Formulations for nasal drug delivery often rely on water sorption to adhere to the mucosa, which also causes a higher water gradient over the tissue and subsequent dehydration.
Abdullah Ali   +6 more
doaj   +1 more source

Estimation of dehydration of skin by refractometric method using optical clearing agents

open access: yesJournal of Biomedical Photonics & Engineering, 2019
Optical methods with highly sensitive to water content are important for the development of new diagnostic and therapeutic methods in medicine. The paper presents a quantitative assessment of the dehydration of skin when using optical clearing agents ...
Ekaterina N. Lazareva   +4 more
doaj   +1 more source

Hydration phase diagram for sodium cobalt oxide Na0.3CoO2*yH2O [PDF]

open access: yesMaterial Research Bulletin vol. 40/4 (2005), p. 665-670, 2004
The hydration phase diagram for sodium cobalt oxyhydrate, Na0.3CoO2*yH2O (y=0, 0.6, 1.3), was determined as a function of relative humidity at 298K. It is found that greater than 75% relative humidity is needed for complete hydration of anhydrous Na0.3CoO2 to the superconducting phase Na0.3CoO2*1.3H2O.
arxiv  

Light‐Triggered Protease‐Mediated Release of Actin‐Bound Cargo from Synthetic Cells

open access: yesAdvanced Biology, EarlyView.
TEV Prtoease‐mediated Releasable Actin‐binding Protein (TRAP) is a protein‐based platform consisting of a cargo tightly bound to reconstituted actin networks in synthetic cells which can be proteolyticly released from the bound actin, followed by its secretion through membrane translocation mediated by a cell‐penetrating peptide.
Mousumi Akter   +3 more
wiley   +1 more source

Activation of SIRT1 Reduces Renal Tubular Epithelial Cells Fibrosis in Hypoxia Through SIRT1‐FoxO1‐FoxO3‐Autophagy Pathway

open access: yesAdvanced Biology, EarlyView.
Hypoxia promotes the epithelial‐mesenchymal transition (EMT) of renal tubular epithelial cells via the SIRT1‐FoxO1‐FoxO3‐autophagy pathway, thereby resulting in the fibrosis of renal tubular epithelial cells. Activation of SIRT1 or induction of autophagy inhibits this process, alleviating hypoxia‐induced fibrosis.
Guangyu Wang   +6 more
wiley   +1 more source

Interstitial cells and neurons respond to variations in hydration [PDF]

open access: yesarXiv, 2020
Dehydration and brain interstitial fluid alterations associate to cognitive dysfunction. We now explore whether changes in matrix hydration are a possible common signal for modulation of water-transfer rates and neuron function.
arxiv  

RhoA and Rac1 as Mechanotransduction Mediators in Colorectal Cancer

open access: yesAdvanced Biology, EarlyView.
Analysing RhoA and Rac1 protein levels in Colorectal cancer (CRC) samples under mechanical strain highlights their potential as diagnostic markers. Monitoring their activity could offer valuable insights into how cancer spreads, paving the way for new approaches to better understand and diagnose colorectal cancer.
Sharda Yadav   +5 more
wiley   +1 more source

Organic carbonates synthesis improved by pervaporation for CO2 utilisation

open access: yesGreen Processing and Synthesis, 2019
This work is focused on the synthesis of organic carbonates from CO2 and ethanol. A parametric study of the synthesis of diethyl carbonate from ethanol is performed in a 100 mL batch reactor.
Décultot Marie   +3 more
doaj   +1 more source

Toward Design Principles for Biomolecular Condensates for Metabolic Pathways

open access: yesAdvanced Biology, EarlyView.
Biomolecular condensates are membrane‐less compartments found through‐out nature which can serve as reaction crucibles for biochemical processes. This review explores the design strategies underlying how condensates can be used in biotechnology to enhance multistep enzyme cascades including enhancement by mass action and substrate channeling, and ...
Alain A.M. André   +3 more
wiley   +1 more source

Unconventional application of the Mitsunobu reaction: Selective flavonolignan dehydration yielding hydnocarpins

open access: yesBeilstein Journal of Organic Chemistry, 2016
Various Mitsunobu conditions were investigated for a series of flavonolignans (silybin A, silybin B, isosilybin A, and silychristin A) to achieve either selective esterification in position C-23 or dehydration in a one-pot reaction yielding the ...
Guozheng Huang   +5 more
doaj   +1 more source

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