Results 121 to 130 of about 276 (148)

Ozonolysis of 7-dehydrocholesterol acetate peroxide

Tetrahedron Letters, 1979
Abstract Secodione 3 and hemiacetal 4 from ozonolysis of peroxide 2 were obtained. A tentative mechanism of their formation is proposed.
J. Gumułka, W.J. Szczepek, Z. Wielogórski   +2 more
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HPLC analysis of desmosterol, 7‐dehydrocholesterol, and cholesterol

Lipids, 1989
AbstractA simple and sensitive method to analyzed mixtures of desmosterol, 7‐dehydrocholesterol and cholesterol is described. The method involves the oxidative conversion of the sterols with cholesterol oxidase, followed by high performance liquid chromatographic (HPLC) analysis.
E H, Goh, S M, Colles, K D, Otte
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The preparation of radioactive 7-dehydrocholesterol

Steroids, 1963
The preparation of radioactive 7-dehydrocholesterol (5,7-cholestadien-3 BETA -ol) by procedures that utilize milligram quantities of cholesterol as starting material is described. The isocaproate adaptation of the allylic bromination of cholesterol with N-bromosuccinimide followed by dehydrobromination was employed and found to be amenable to a scale ...
B.D. Kulkarni, G. Blondin, W.R. Nes
openaire   +1 more source

Skin content of 7-dehydrocholesterol in patients with malabsorption

Nutrition, 1997
The mechanism for the development of vitamin D deficiency in patients with malabsorption remains unclear. We wished to examine the hypothesis that one factor was a reduced skin content of 7-dehydrocholesterol, the precursor for the formation of vitamin D in the presence of ultraviolet radiation.
C R, Paterson, J P, Moody, C R, Pennington   +2 more
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Secretory production of 7‐dehydrocholesterol by engineered Saccharomyces cerevisiae

Biotechnology Journal, 2023
AbstractBackground7‐Dehydrocholesterol (7‐DHC) can be directly converted to vitamin D3 by UV irradiation and de novo synthesis of 7‐DHC in engineered Saccharomyces cerevisiae has been recognized as an attractive substitution to traditional chemical synthesis.
Xia Ke, Zi‐Hao Pan, Hong‐Fei Du, Yi Shen, Ji‐Dong Shen, Zhi‐Qiang Liu, Yu‐Guo Zheng   +6 more
openaire   +2 more sources

Engineered yeast for efficient de novo synthesis of 7‐dehydrocholesterol

Biotechnology and Bioengineering, 2022
AbstractThe synthesis of vitamin D3 precursor 7‐dehydrocholesterol (7‐DHC) by microbial fermentation has much attracted attention owing to its advantages of environmental protection. In this study, Saccharomyces cerevisiae was engineered for a de novo biosynthesis of 7‐DHC.
Lisha Qu, Xiang Xiu, Guoyun Sun, Chenyang Zhang, Haiquan Yang, Yanfeng Liu, Jianghua Li, Guocheng Du, Xueqin Lv, Long Liu   +9 more
openaire   +2 more sources

Photometabolism of 7-dehydrocholesterol to previtamin D3 in skin

Biochemical and Biophysical Research Communications, 1977
Abstract The photometabolism of [3α-3H]-7-dehydrocholesterol in skin was studied in groups of rats exposed to ultraviolet irradiation. The major photolytic product was identified as previtamin D3 by its identical migration with authentic previtamin D3 on high-pressure liquid chromatography.
M F, Holick, J E, Frommer, S C, McNeill, N M, Richtand, J W, Henley, J T, Potts   +5 more
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ChemInform Abstract: OZONOLYSIS OF 7‐DEHYDROCHOLESTEROL ACETATE PEROXIDE

Chemischer Informationsdienst, 1980
AbstractDie Ozonolyse des bekannten Dehydrocholesterinacetat‐peroxides (I) liefert die Folgeprodukte (II)‐(IV), die isoliert und identifiziert werden.
J. GUMULKA, W. J. SZCZEPEK, Z. WIELOGORSKI   +2 more
openaire   +1 more source

7-Dehydrocholesterol is an endogenous suppressor of ferroptosis

Nature
Ferroptosis is a form of cell death that has received considerable attention not only as a means to eradicate defined tumour entities but also because it provides unforeseen insights into the metabolic adaptation that tumours exploit to counteract phospholipid oxidation1,2.
Florencio Porto Freitas, Hamed Alborzinia, Ancély Ferreira dos Santos, Palina Nepachalovich, Lohans Pedrera, Omkar Zilka, Alex Inague, Corinna Klein, Nesrine Aroua, Kamini Kaushal, Bettina Kast, Svenja M. Lorenz, Viktoria Kunz, Helene Nehring, Thamara N. Xavier da Silva, Zhiyi Chen, Sena Atici, Sebastian G. Doll, Emily L. Schaefer, Ifedapo Ekpo, Werner Schmitz, Aline Horling, Peter Imming, Sayuri Miyamoto, Ann M. Wehman, Thiago C. Genaro-Mattos, Karoly Mirnics, Lokender Kumar, Judith Klein-Seetharaman, Svenja Meierjohann, Isabel Weigand, Matthias Kroiss, Georg W. Bornkamm, Fernando Gomes, Luis Eduardo Soares Netto, Manjima B. Sathian, David B. Konrad, Douglas F. Covey, Bernhard Michalke, Kurt Bommert, Ralf C. Bargou, Ana Garcia-Saez, Derek A. Pratt, Maria Fedorova, Andreas Trumpp, Marcus Conrad, José Pedro Friedmann Angeli   +46 more
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The site of 7-dehydrocholesterol ultraviolet photolysis in domestic fowls

Acta Histochemica, 1983
The site of the photolytic reaction leading to Vitamin D3 in fowls integument has been investigated by histochemical and biochemical analysis. The Vitamin D3 precursor, 7-dehydrocholesterol, is synthetized and stored mainly in the uropygial gland and in the same localization several amount of Vitamin D3 may be biochemically detected.
B, Uva, A, Mandich, M, Vallarino
openaire   +2 more sources