Results 131 to 140 of about 276 (148)
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Inhibition of human fibroblasts sphingomyelinase by cholesterol and 7-dehydrocholesterol
Biochemical and Biophysical Research Communications, 1981Abstract An inhibition of human fibroblast sphingomyelinase by cholesterol and 7-dehydrocholesterol is shown. This effect is obtained for cholesterol and 7-dehydrocholesterol/sphingomyelin molar ratios above 0.1. Diffusion measurements performed on mixed liposomes demonstrated for cholesterol/sphingomyelin and 7-dehydrocholesterol/sphingomyelin molar
J C, Maziere +5 more
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Evaluation of cytotoxic effects of 7-dehydrocholesterol on melanoma cells
Free Radical Biology and Medicine, 2014Ultraviolet radiation is the main cause of skin cancers, and melanoma is the most serious form of tumor. There is no therapy for advanced-stage melanoma and its metastasis because of their high resistance to various anticancer therapies. Human skin is an important metabolic organ in which occurs photoinduced synthesis of vitamin D3 from 7 ...
GELZO, MONICA +7 more
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7-Dehydrocholesterol: A sterol shield against an iron sword
Molecular CellLi et al. and Freitas et al. recently identified 7-dehydrocholesterol (7-DHC), a sterol produced through the cholesterol biosynthetic pathway, as a lipid-soluble antioxidant that protects cells from ferroptosis, a cell death pathway triggered by iron-catalyzed phospholipid peroxidation.1,2.
Shaojie Cui, Jin Ye
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Intestinal sterols. I. Δ7-cholestenol and 7-dehydrocholesterol in feces
Archives of Biochemistry and Biophysics, 19551. 1. Fecal sterols from rats on a fat-free diet were found to contain substantial amounts of fast-acting sterols. Chromatography of the unsaponifiable matter resulted in the isolation of Δ7-cholestenol, cholesterol, and coprosterol, and in the identification of 7-dehydrocholesterol. 2. 2.
Wells, W W, Coleman, D L, Baumann, C A
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Effects of Tween 80 on liver microsomal 7-dehydrocholesterol reductase
Biochemical and Biophysical Research Communications, 1978Abstract Enzymatic conversion of 7-dehydrocholesterol to cholesterol by liver microsomes was increased by addition of Tween 80. This increase was proportional to Tween 80 concentration, and reached its maximum of 250% of baseline activity after addition of 300 μg/ml of Tween 80.
M V, Srikantaiah, S, Assef, R J, Morin
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Probing the Biexponential Dynamics of Ring-Opening in 7-Dehydrocholesterol
The Journal of Physical Chemistry A, 2016Our prior discovery of a novel biexponential photochemical ring-opening in 7-dehydrocholesterol (DHC) to previtamin D3 [ Tang J. Chem. Phys. 2011 , 134 , 104503 ] is further explored with ultrafast transient absorption spectroscopy, and the results are compared with recently reported high-level theoretical calculations.
Broc D, Smith +2 more
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Thermal isomerization of ergosterol and dehydrocholesterol
The Journal of Organic Chemistry, 1968J, Wolinsky, L L, Baxter, J, Hamsher
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7-Dehydrocholesterol protects membrane phospholipids from oxidation
Free Radical Biology and Medicine, 2022Alex Inague +3 more
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