Cerebral Inflammation in an Animal Ischemia–Reperfusion Model Comparing Histidine-Tryptophan-α-Ketoglutarate and Del Nido Cardioplegia [PDF]
Brain injury and cerebral inflammation are frequent complications following cardiopulmonary bypass (CPB) resulting in neurocognitive dysfunction, encephalopathy, or stroke.
Kristin Klaeske +8 more
doaj +4 more sources
Modified Del Nido “microplegia” reduces intraoperative, postoperative, and total blood productsCentral MessagePerspective [PDF]
Objectives: Previous studies have shown that Buckberg microplegia reduces the need for intraoperative blood transfusion by minimizing hemodilution. However, this approach has been largely understudied in the context of Del Nido cardioplegia.
Abigayle B. Simon, BS +9 more
doaj +2 more sources
Del Nido versus warm blood cardioplegia in adult patients with a low ejection fraction
Background Del Nido cardioplegia was recently introduced to adult cardiac surgery with encouraging results. The effect of Del Nido cardioplegia in patients with low ejection fraction (EF) has not been thoroughly evaluated. The objective of this study was
Claudio Pragliola, Khaled Algarni
exaly +2 more sources
Single-dose modified bloodless del Nido cardioplegia for minimally invasive cardiac surgery [PDF]
BackgroundRecent studies demonstrated satisfactory results of del Nido cardioplegia in minimally invasive cardiac surgery (MICS). We aimed to evaluate the efficacy of our modified “bloodless” del Nido cardioplegia in MICS compared to the histidine ...
Heemoon Lee, Jihoon Kim, Jae Suk Yoo
doaj +2 more sources
Comparing del Nido and St. Thomas II cardioplegia in a rat ischemia–reperfusion model: Histopathology, mitochondria, and TEM analysis [PDF]
Myocardial ischemia–reperfusion (IR) injury remains a major challenge in cardiac surgery, and comparative histological and ultrastructural data on cardioplegia solutions are limited. This study compared the myocardial protective effects of St. Thomas II
Burak Toprak +3 more
doaj +2 more sources
Comparison of routine del Nido cardioplegia vs two types of modified del Nido cardioplegias for myocardial protection among patients undergoing coronary artery bypass grafting (CABG) surgeries: A randomized double-blind clinical trial [PDF]
Background: The del Nido cardioplegia solution is a widely used method for myocardial protection in various settings. However, there is limited evidence of its effectiveness in adult cardiac surgery, and the baseline solution, Plasma Lyte A, is not ...
Ali Babar +8 more
doaj +2 more sources
Comparative analysis of del Nido cardioplegia versus blood cardioplegia in isolate coronary artery bypass grafting [PDF]
Background This study examined the efficacy of del Nido cardioplegia compared with traditional blood cardioplegia in adult cardiac surgery for isolated coronary artery bypass grafting by evaluating the early postoperative outcomes. Methods A total of 119
Soojin Lee +6 more
doaj +2 more sources
Modified Del Nido Cardioplegia with a 1:4 Crystalloid-to-Blood Ratio Versus Blood-Based St. Thomas Cardioplegia in Isolated Aortic Valve Replacement [PDF]
The aim of this study was to retrospectively compare modified Del Nido and blood-based St. Thomas cardioplegia in adult patients undergoing isolated aortic valve replacement (AVR).
Peter Jakub +7 more
doaj +2 more sources
Traditional vs. modified Ringer lactate-based del Nido cardioplegia impacts on clinical outcomes in patients undergoing coronary artery bypass grafting: Results from a prospective, randomized, blinded trial [PDF]
Introduction: Myocardial protection with cardioplegia is a crucial approach to mitigate myocardial damage during coronary bypass grafting surgery (CABG) with cardiopulmonary bypass (CPB).
Kachoueian Naser +7 more
doaj +2 more sources
Outcomes of Del Nido and hyperkalemic blood cardioplegia in adult cardiac surgery with prolonged aortic cross-clamp times★ [PDF]
Background: The utility and uptake of Del Nido cardioplegia in adult cardiac surgery is rapidly increasing. Cases with prolonged aortic cross-clamp times necessitate multi-dosing however an understanding of safe ischaemic times and definitive guidelines ...
Szpytma Malgorzata +7 more
doaj +2 more sources

