Results 231 to 240 of about 643,838 (299)

Effects of the angle of head‐down tilt on dynamic cerebral autoregulation during combined exposure to cephalad fluid shift and mild hypercapnia

open access: yesExperimental Physiology, EarlyView.
Abstract Astronauts experience combined exposure to a cephalad fluid shift and mild hypercapnia during space missions, potentially contributing to health problems. Such combined exposure may weaken dynamic cerebral autoregulation. The magnitude of cephalad fluid shift varies between individuals, and dynamic cerebral autoregulation may be affected more ...
Tomokazu Kato   +2 more
wiley   +1 more source

Uncovering the impact of the cardiovascular system on cerebrovascular health using MRI

open access: yesExperimental Physiology, EarlyView.
Abstract Human cerebrovasculature is finely tuned to enable local changes in blood flow to meet the brain's demands, whilst protecting the brain from systemic changes in blood pressure, both acutely during a heartbeat and chronically over time. This review summarises cerebrovascular structure and function, their role in disease and neurodegeneration ...
Ian D. Driver, Kevin Murphy
wiley   +1 more source

Optimizing cerebrovascular endothelial health through shear stress modulation

open access: yesExperimental Physiology, EarlyView.
Abstract The endothelium plays a pivotal role in regulating cerebrovascular blood flow, and its dysfunction increases the risk of cerebrovascular disease. Endothelial shear stress, a primary mechanical stimulus for endothelial nitric oxide production, is a key modulator of vascular adaptation.
Erika Iwamoto   +2 more
wiley   +1 more source

Linking dynamic cerebral autoregulation and inhibitory executive function: Role of modifiable behaviours

open access: yesExperimental Physiology, EarlyView.
Abstract Dynamic cerebral autoregulation (dCA) stabilises cerebral blood flow (CBF) against rapid fluctuations in perfusion pressure and may serve as a key physiological mediator of cognitive function. Inhibitory executive function, a core domain essential for goal‐directed behaviour, is influenced by modifiable lifestyle factors such as physical ...
Hayato Tsukamoto, Damian M. Bailey
wiley   +1 more source

Time‐course analysis of cerebral circulation and cardiorespiratory responses to acute central blood volume reduction in healthy young males

open access: yesExperimental Physiology, EarlyView.
Abstract Central blood volume (CBV) reduction challenges circulatory and respiratory homeostasis, particularly during the initial compensatory phase (0–2 min), when rapid physiological adaptations occur. In this study, we examined dynamic cardiorespiratory responses to CBV reduction using lower‐body negative pressure (LBNP) in 11 healthy young males ...
Marina Feeley   +7 more
wiley   +1 more source

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