Results 101 to 110 of about 1,254,509 (299)
The endosomal sorting complex required for transport repairs the membrane to delay cell death. [PDF]
Front Oncol, 2022 Yang Y, Wang M, Zhang YY, Zhao SZ, Gu S.
europepmc +1 more source
Channelization architecture for wide-band slow light in atomic vapors
, 2005 We propose a ``channelization'' architecture to achieve wide-band electromagnetically induced transparency (EIT) and ultra-slow light propagation in atomic Rb-87 vapors.
Bashkansky, Mark +3 more
core +1 more source
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
A Delay-Cell-Controlled VCO Design for Unipolar Single-Gate Enhancement-Mode TFT Technologies. [PDF]
Micromachines (Basel), 2022 Li B, Wei S, Zhao M, Chen R, Wu Z, Xu Y.
europepmc +1 more source
Fundamentals of Inter-cell Overhead Signaling in Heterogeneous Cellular Networks
, 2011 Heterogeneous base stations (e.g. picocells, microcells, femtocells and distributed antennas) will become increasingly essential for cellular network capacity and coverage. Up until now, little basic research has been done on the fundamentals of managing
Andrews, Jeffrey G. +2 more
core +1 more source
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Molecular Oncology, EarlyView.Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
Delay-Locked Loop Using 4 Cell Delay Line with Extended Inverters
International Journal of Electronics and Electrical Engineering, 2014 A proposed delay-locked loop (DLL) circuit that uses 4 cell delay line with extended inverters is proposed, designed and simulated in 180nm CMOS process technology. This design can be applied to microprocessors, memory, and communication IC applications whose timing relationships (delay) are essential.
Jefferson A. Hora +2 more
openaire +1 more source
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Delayed Metastasis of Renal Cell Carcinoma
Internal Medicine, 2022 Umeoka, Ayato, Aso, Shotaro
openaire +3 more sources
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source