Results 31 to 40 of about 29,531 (259)

Moment Estimation for Uncertain Delay Differential Equations via the Composite Heun Scheme

Mathematics
As an important mathematical model actuated by the Liu process, uncertain delay differential equations depict the development of system dynamics. In the applications of uncertain delay differential equations, parameter estimation plays a key role. In the
Shaoling Zhou, Huimin Zhang, Chiteng Liu, Xiaosheng Wang   +3 more
doaj   +1 more source

Delay Differential Equations in Sequence Spaces

Communications in Advanced Mathematical Sciences, 2019
The standard  delay equations are newly studied in the context of classical separable Banach Sequence Spaces.  As a classical solution is shown to exist, the associated semigroup and its infinitesimal generator are found, and some important properties of
Luis Gerardo Mármol, Carmen Judith Vanegas   +1 more
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Advanced Study on the Delay Differential Equation y′(t) = ay(t) + by(ct)

Mathematics, 2022
Many real-world problems have been modeled via delay differential equations. The pantograph delay differential equation y′(t)=ay(t)+byct belongs to such a set of delay differential equations.
Aneefah H. S. Alenazy, Abdelhalim Ebaid, Ebrahem A. Algehyne, Hind K. Al-Jeaid   +3 more
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Numerical Study for Time Delay Multistrain Tuberculosis Model of Fractional Order

Complexity, 2017
A novel mathematical fractional model of multistrain tuberculosis with time delay memory is presented. The proposed model is governed by a system of fractional delay differential equations, where the fractional derivative is defined in the sense of the ...
Nasser Hassan Sweilam, Seham Mahyoub Al-Mekhlafi, Taghreed Abdul Rahman Assiri   +2 more
doaj   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source

Oscillations of First Order Linear Delay Differential Equations with positive and negative coefficients

مجلة بغداد للعلوم, 2011
Oscillation criteria are obtained for all solutions of the first-order linear delay differential equations with positive and negative coefficients where we established some sufficient conditions so that every solution of (1.1) oscillate.
Baghdad Science Journal
doaj   +1 more source