Results 101 to 110 of about 700,958 (287)
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Boundary controllability of impulsive nonlinear fractional delay integro-differential system
Cogent Engineering, 2016 By using the strongly continuous semigroup theory and the Banach contraction principle, we study the boundary controllability of time varying delay impulsive nonlinear fractional integrodifferential system in Banach spaces.
Hamdy M. Ahmed
doaj +1 more source
On linear generalized neutral differential delay systems
Journal of the Franklin Institute, 2009 In this paper, the class of linear generalized neutral differential delay systems with time-invariant coefficients is studied. These kinds of systems are inherent in many physical and engineering phenomena. Using the matrix pencil theory, we decompose it into five subsystems, whose solutions are obtained.
Athanasios A. Pantelous +1 more
openaire +2 more sources
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Permanence for a class of non-autonomous delay differential systems
Electronic Journal of Qualitative Theory of Differential Equations, 2018 We are concerned with a class of $n$-dimensional non-autonomous delay differential equations obtained by adding a non-monotone delayed perturbation to a linear homogeneous cooperative system of delay differential equations.
Teresa Faria
doaj +1 more source
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
Oscillatory and asymptotic properties of fractional delay differential equations
Electronic Journal of Differential Equations, 2019 This article discusses the oscillatory and asymptotic properties of a test delay differential system involving a non-integer derivative order. We formulate corresponding criteria via explicit necessary and sufficient conditions that enable direct ...
Jan Cermak, Tomas Kisela
doaj
Approximate controllability of neutral functional differential system with unbounded delay
International Journal of Mathematics and Mathematical Sciences, 2001 We consider a class of control systems governed by the neutral functional differential equation with unbounded delay and study the approximate controllability of the system. An example is given to illustrate the result.
Jong Yeoul Park, Sang Nam Kang
doaj +1 more source
Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
Molecular Oncology, EarlyView.We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source