Results 121 to 130 of about 56,045 (301)

PATHOLOGICAL CHANGES IN MICE TREATED WITH CYCLOPHOSPHAMIDE AND EXOGENOUS DNA

Вавиловский журнал генетики и селекции, 2014
The synergic action of the cytostatic drug cyclophosphamide (CP) and fragmented exogenous DNA causes illness and death in mice (Dolgova et al., 2011–2013).
E. V. Dolgova, V. P. Nikolin, N. A. Popova, A. S. Proskurina, K. E. Orishchenko, E. A. Alyamkina, Ya. R. Efremov, S. I. Baiborodin, E. R. Chernykh, A. A. Ostanin, S. S. Bogachev, T. S. Gvozdeva, E. M. Malkova, O. S. Taranov, V. A. Rogachev, A. S. Panov, S. N. Zagrebelnyi, M. A. Shurdov   +17 more
doaj  

Cytotoxic effects of rabbit anti-thymocyte globulin preparations on primary human thymic epithelial cells

, 2019
BACKGROUND: Graft-versus-host disease (GvHD) presents a major cause for morbidity and mortality after allogeneic hematopoietic stem cell transplantation (alloHSCT).
Becker, S.C., Thiel, A., Kaebisch, E.M., Szyska, M., Cho, M.Y., Olfe, L.I., Volk, H.D., Bullinger, L., Oh, Y.S., Gillissen, B., Reinke, P., Na, I.K.   +11 more
core   +1 more source

Unraveling 4‐Phenylbutyrate's Therapeutic Role in SLC6A1 Disorders: Pharmacochaperoning Over HDAC Inhibition

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw, Karishma Randhave, Ekta Anand, Ziang (Debbie) Song, Wangzhen Shen, Jing‐Qiong Kang   +5 more
wiley   +1 more source

The influence of the granulated bacterial preparations of complex action on development of some coniferous plants

, 2007
Гранульовані бактеріальні препарати комплексної дії на основі фосфатмобілізувальних, азотфіксувальних мікроорганізмів і глинистих мінералів спричиняють стимулювальний вплив на розвиток хвойних рослин.
Захарченко, В.О, Курдиш, І.К., Рой, А.О., Царенко, І.Ю.   +3 more
core   +1 more source

Action of humic Acid Preparations on Leaf Development, Mineral Elements Contents and Chloroplast Ultrastructure of Ryegrass Plants

, 1985
6 pages, figures, and tables statistics.The action of humic acid preparations obtained from straw or peal fermented under controlled conditions on mineral elements contents, área and dimensions of leaves, and ultrastructure of chloroplasts of Lolium ...
Rapsch, Sonia, Fortún García, Consuelo, Ascaso, Carmen   +2 more
core  

Peripheral Neutrophil Activation and Extracellular Trap Formation in Amyotrophic Lateral Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
Markers of neutrophil activation are increased in plasma during ALS, and markers of NET formation associate with ALS survival. ABSTRACT Objectives Peripheral neutrophil levels in amyotrophic lateral sclerosis (ALS) inversely correlate with survival, suggesting a role for neutrophils in disease progression.
Lillia A. Baird, Haley McQuown, Jihyun Park, Samuel J. Teener, Ian F. Webber‐Davis, Andrew D. Carter, Dae‐Gyu Jang, Eva L. Feldman, Stephen A. Goutman, Benjamin J. Murdock   +9 more
wiley   +1 more source

THE COMPERATIVE EVALUATION OF AMINOSTIGMINE AS THE MEANS FOR TREATMENT OF THE ACUTE POISONINGS BY PREPARATIONS OF THE CHOLINOLYTIC ACTION

, 1992
Examine have been 169 men at the age of 15 to 58 years old with acute poisonings by the preparations of the anticholineric action. The purpose of the work: the clinic study of the efficiency of the new medicinal preparation, and some mechanisms of its ...
Velikova, Varvara Dmitrievna
core  

Plasma EV Proteomics Identifies ECM Remodeling and Inflammatory Proteins LUM and C7 as Candidate Biomarkers in FSHD

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Facioscapulohumeral muscular dystrophy (FSHD) is one of the most debilitating and common muscular dystrophies. Despite its severity, no approved therapy exists for FSHD patients. However, several therapeutic candidates are currently under development, and some have recently entered clinical trials, marking the need for reliable ...
Mustafa Bilal Bayazit, Chiranth K. Nagaraj, Jackson S. Newell, Kim Truc Nguyen, Xilal Y. Rima, Jacob Doon‐Ralls, Eduardo Reátegui, Jeffrey M. Statland, Rabi Tawil, Kevin M. Flanigan, Scott Q. Harper, Nizar Y. Saad   +11 more
wiley   +1 more source

Biological preparations with different mechanisms of action for protecting potato against fungal diseases [PDF]

, 2006
Mycological analysis throughout the vegetation period of potato (Solanum tuberosum) made it possible to study in detail the structure of the micromycete community, to determine typical dominant (frequency, more than 60%), typical common (frequency, 30 to
Kulikov S., Nemtsev S., Alimova F., Zakharova N., Varlamov V.   +4 more
core  

Prominent Movement Disorders in RNU2‐2‐Related Spliceosomopathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Pediatric movement disorders often overlap with neurodevelopmental diseases, suggesting shared molecular mechanisms. Variants in small nuclear RNA (snRNA) genes encoding spliceosome components have recently been associated with neurodevelopmental disorders, termed “RNUopathies.” We analyzed genome sequencing data from 14 patients with ...
Magdalena Krygier, Ugo Sorrentino, Matias Wagner, Marta Zawadzka, Anna Lemska, Maria Mazurkiewicz‐Bełdzińska, Michael Zech   +6 more
wiley   +1 more source