A biocompatible hydrogel coating with tissue‐like mechanics and reversible dissolution triggered by a mild, physiologically compatible temperature drop (≈37°C → ≈25°C) was developed for the transient encapsulation of implantable devices. The physically crosslinked methylcellulose, polyethylene glycol and polyacrilic acid (MC/PEG/PAA) hydrogel ...
Francesca Persano +14 more
wiley +1 more source
Functional mechanism and clinical implications of miR-455-5p in delayed fracture healing. [PDF]
Ma Y, Zhang J, He L, Xu H, Zhao X.
europepmc +1 more source
We developed an implantable dual‐drug depot using GelMA for bone metastasis treatment, co‐delivering MSA‐2 and αB7‐H3‐loaded CaCO3 microparticles. Sustained release from GelMA scaffold enables MSA‐2 to activate STING signaling and enhance T‐cell infiltration and activation, while sequentially released αB7‐H3 blocks MSA‐2‐induced B7‐H3 upregulation ...
Qijun Lin +10 more
wiley +1 more source
Serum DLX6-AS1 and miR-141-3p as early diagnostic biomarkers and regulators of delayed fracture healing (DFH). [PDF]
Zhang M, Chen G, Ruan Y, Zhang J.
europepmc +1 more source
Disturbed remodeling and delayed fracture healing in pediatric pycnodysostosis patients. [PDF]
Grewal S +3 more
europepmc +1 more source
Development‐based In Vivo Bioreactor Strategy for Challenging Senescent Bone Reconstruction
We present a development‐based in vivo bioreactor strategy to generate rejuvenated bone grafts (vBR‐Bone) within aged hosts. By enclosing vBR‐Bone fragments within an asymmetric biomimetic periosteum, segmental femoral defects in aged mice were successfully repaired within 6 weeks. Mechanistically, the multifactors of vBR‐Bone reconstitute a remodeling
Wenchao Zhang +9 more
wiley +1 more source
The use of regenerative technologies for treatment of delayed fracture union in patient with menopausal osteoporosis. [PDF]
Maslennikov S +2 more
europepmc +1 more source
Continuous infusion of PTH1-34 delayed fracture healing in mice. [PDF]
Yukata K +8 more
europepmc +1 more source
Case Report of the Unusual Presentation of Stridor in an Elderly Patient Following a Cervical Fracture [PDF]
Dearden, Rachel +3 more
core
Breaking the Toughness‐Stretchability Trade‐Off in Hydrogels with Dynamic Hydrogen Bonding
A novel nanocomposite hydrogel architecture overcomes the inherent conflict between toughness and stretchability by integrating uniformly dispersed aminopropyl‐hybrid‐phyllosilicate nanosheets within a polyacrylamide matrix. This design leverages a dynamic hydrogen‐bonding network to facilitate efficient energy dissipation and self‐recovery.
Yining Gao +3 more
wiley +1 more source

