Results 161 to 170 of about 154,529 (215)
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Seminars in Musculoskeletal Radiology, 2022
Abstract Physiologic bone healing involves numerous parameters, such as microstability, fracture morphology, or tissue perfusion, to name just a few. Slight imbalances or a severe impairment of even one of these factors may, as the figurative weakest link in the chain, crucially or completely inhibit the regenerative potential of a ...
Paul Mick, Christian Fischer
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Abstract Physiologic bone healing involves numerous parameters, such as microstability, fracture morphology, or tissue perfusion, to name just a few. Slight imbalances or a severe impairment of even one of these factors may, as the figurative weakest link in the chain, crucially or completely inhibit the regenerative potential of a ...
Paul Mick, Christian Fischer
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Unbiased gene expression analysis of the delayed fracture healing observed in Zucker diabetic fatty rats [PDF]
Bone and Joint Research, 2023 Aims: Impaired fracture repair in patients with type 2 diabetes mellitus (T2DM) is not fully understood. In this study, we aimed to characterize the local changes in gene expression (GE) associated with diabetic fracture. We used an unbiased approach to
Jonghoo Sung +2 more
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Delayed Fracture Healing in Diabetics with Distal Radius Fractures
Acta chirurgiae orthopaedicae et traumatologiae Cechoslovaca, 2015Diabetics may have an increased fracture risk, depending on disease duration, quality of metabolic adjustment and extent of comorbidities, and on an increased tendency to fall. The aim of this retrospective one-centre study consisted in detecting differences in fracture healing between patients with and without diabetes mellitus.
S, Pscherer +5 more
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Mechanisms Underlying Normal Fracture Healing and Risk Factors for Delayed Healing
Current Osteoporosis Reports, 2019Substantial advances have been made in understanding the biological basis of fracture healing. Yet, it is unclear whether the presence of osteoporosis or prior or current osteoporosis therapy influences the healing process or is associated with impaired healing.
Cheng, Cheng, Dolores, Shoback
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Bone fracture healing is delayed in splenectomic rats
Life Sciences, 2017Splenectomy is sometimes required in bone fracture patients. The present study aims to investigate the effect of splenectomy on fracture healing in rats.Rats underwent osteotomy were subjected to splenectomy. The effects of splenectomy were evaluated at day 0, 3, 15 and 30 post-fracture.
Wan'an, Xiao +3 more
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Delayed fracture healing in tetranectin-deficient mice
Journal of Bone and Mineral Metabolism, 2013Tetranectin is a plasminogen-binding protein that enhances plasminogen activation, which has been suggested to play a role in tissue remodeling. Recently, we showed that tetranectin has a role in the wound-healing process. In this study, we investigated whether tetranectin plays a role in fracture healing. The fracture-healing process was studied using
Kousuke, Iba +8 more
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A murine delayed-union fracture healing model [PDF]
, 2008 Da das Mäusegenom entschlüsselt wurde, wäre es vorteilhaft, ein Mausmodel zur verzögerten Frakturheilung zu besitzen, um die molekularen Mechanismen und Behandlung dieser noch bestehenden Komplikation der Knochenheilung zu verstehen. Das Periost spielt im Bezug auf die Blutversorgung des Knochens während der Frakturheilung und als Quelle von ...
Wissing, Sandra
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TGF-β1 as a marker of delayed fracture healing
Bone, 2005Mitogens of the TGF-beta superfamily have been shown to be crucial local and systemic regulatory molecules involved in fracture healing. However, there exists only little information about systemic regulation of bone regeneration by growth factors and no reports comparing serum levels of bone growth factors between normal and failed fracture healing ...
G, Zimmermann +6 more
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Downregulation of regulatory T cell function in patients with delayed fracture healing
Clinical and Experimental Pharmacology and Physiology, 2018Hui Jiang, Yicun Wang, Jianning Zhao
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Molecular and Cellular Endocrinology, 2021
Fracture healing is a complicated process affected by many factors, such as inflammatory responses and angiogenesis. Omentin-1 is an adipokine with anti-inflammatory properties, but whether omentin-1 affects the fracture healing process is still unknown.
Shiyao Feng +20 more
semanticscholar +1 more source
Fracture healing is a complicated process affected by many factors, such as inflammatory responses and angiogenesis. Omentin-1 is an adipokine with anti-inflammatory properties, but whether omentin-1 affects the fracture healing process is still unknown.
Shiyao Feng +20 more
semanticscholar +1 more source