Results 151 to 160 of about 586,059 (333)

α‐Synuclein Pathology Spreads in a Midbrain–Hindbrain Assembloid Model

Advanced Science, EarlyView.
A novel midbrain–hindbrain assembloid model demonstrates the spread of α‐synuclein pathology, a hallmark of Parkinson's disease, mimicking Braak's hypothesis. This model reveals how pathology propagates from the hindbrain to the midbrain, inducing synaptic changes and early signs of neuronal vulnerability. It offers an innovative platform for exploring
Gemma Gomez‐Giro, Daniela Frangenberg, Daniela Vega, Alise Zagare, Kyriaki Barmpa, Paul M. A. Antony, Graham Robertson, Rahman Sabahi‐Kaviani, Kristian Haendler, Nathalie Kruse, Florentia Papastefanaki, Rebecca Matsas, Malte Spielmann, Regina Luttge, Jens C. Schwamborn   +14 more
wiley   +1 more source

INCREASED LEVELS OF GAL??1???4GLCNAC??2???6 SIALYLTRANSFERASE PRETRANSPLANT PREDICT DELAYED GRAFT FUNCTION IN KIDNEY TRANSPLANT RECIPIENTS1

, 2000
Gro Thorne‐Tjomsland, T Hosfield, James C. Jamieson, Bin Liu, Peter Nickerson, James Gough, David N. Rush, John Jeffery, Rachel M. McKenna   +8 more
openalex   +1 more source

Inhibition of Aberrant Activated Fibroblast‐Like Synoviocytes in Rheumatoid Arthritis by Leishmania Peptide via the Regulation of Fatty Acid Synthesis Metabolism

Advanced Science, EarlyView.
LACK156‐173 is internalized into RA‐FLSs via CAPN2‐mediated endocytosis and inhibits the aggressive phenotype of RA‐FLSs by restoring dysregulated fatty acid synthesis metabolism mediated by overexpressed FASN. The findings suggest that targeting the restoration of fatty acid metabolism could potentially alleviate synovial invasion and joint damage in ...
Jianling Su, Xuemei Fan, Yaoyao Zou, Guangtao Fu, Shiqi Feng, Xiaoxue Wang, Yongmei Yu, Lin Li, Zhenhua Bian, Rongrong Huang, Linmang Qin, Jiping Chen, Qin Zeng, Kai Yan, Caiyue Gao, Zhexiong Lian, Xin Li, Yang Li   +17 more
wiley   +1 more source

LOW KIDNEY REJECTION RATES WITH BASILIXIMAB INDUCTION AND DELAYED INTRODUCTION OF TACROLIMUS FOR PATIENTS WITH DELAYED GRAFT FUNCTION.

, 2000
Benjamin Philosophe, Jeffrey C. Fink, Anne Wiland, Alan C. Farney, Eugene J. Schweitzer, John O. Colonna, Bruce E. Jarrell, Venkatesh Krishnamurthi, Stephen T. Bartlett   +8 more
openalex   +1 more source

Expanded Criteria Donor Kidney Allocation: Marked Decrease in Cold Ischemia and Delayed Graft Function at a Single Center [PDF]

, 2005
Jonathan Carter, Sharon Chan, John P. Roberts, Sandy Feng   +3 more
openalex   +1 more source

Recent Advancements in Lung Cancer Metastasis Prevention Based on Nanostrategies

Advanced Science, EarlyView.
Metastasis is the leading cause of death in patients with lung cancer. Nanomedicine can be used to prepare efficient drug delivery systems owing to their advantages and plays an important role in the synergistic antimetastasis of lung cancer. This comprehensive review summarizes the emerging nanostrategies against lung cancer metastasis based on the ...
Fan Xu, Yao Liu, Zujun Que, Bin Luo, Yun Yang, Yan Li, Zhanxia Zhang, Jianhui Tian   +7 more
wiley   +1 more source

THE EFFECT OF PRESERVATION AND RECIPIENT IMMUNE FACTORS ON DELAYED GRAFT FUNCTION AND ITS SEQUELAE IN CADAVERIC RENAL TRANSPLANTATION.

, 2000
Daniel A. Shoskes, Michael Cecka
openalex   +1 more source

Nanotherapy for Neural Retinal Regeneration

Advanced Science, EarlyView.
Nanotechnology enhances ophthalmic treatments by improving drug delivery and regenerating ocular tissues, combating vision loss from retinal diseases through innovative nano‐systems. This review outlines ocular anatomy, pathology, immune microenvironment, and barriers, detailing nanocarrier characteristics, classification, and preparation methods, and ...
Chuyao Yu, Li Dong, Yujia Lv, Xuhan Shi, Ruiheng Zhang, Wenda Zhou, Haotian Wu, Heyan Li, Yitong Li, Zhou Li, Dan Luo, Wen‐Bin Wei   +11 more
wiley   +1 more source

Effects of Delayed Graft Function on Transplant Outcomes: A Meta-analysis. [PDF]

Transplant Direct, 2023
Li MT, Ramakrishnan A, Yu M, Daniel E, Sandra V, Sanichar N, King KL, Stevens JS, Husain SA, Mohan S.   +9 more
europepmc   +1 more source

DACLIZUMAB PERMITS DELAYED INTRODUCTION OF CALCINEURIN INHIBITORS IN RENAL TRANSPLANT RECIPIENTS AT RISK FOR DELAYED GRAFT FUNCTION.

, 2000
Muralikrishna S. Golconda, Stephen C. Rayhill, Lawrence G. Hunsicker   +2 more
openalex   +1 more source