Results 21 to 30 of about 54,745 (162)

Impact of initial exposure to calcineurin inhibitors on kidney graft function of patients at high risk to develop delayed graft function

Brazilian Journal of Medical and Biological Research, 2006
We conducted a retrospective analysis of the influence of full doses of calcineurin inhibitors [8-10 mg kg-1 day-1 cyclosporine (N = 80), or 0.2-0.3 mg kg-1 day-1 tacrolimus (N = 68)] administered from day 1 after transplantation on the transplant ...
L.A. Silva, C.R. Felipe, S.I. Park, P. Pinheiro-Machado, R. Garcia, M. Franco, S.R. Moreira, H. Tedesco-Silva Jr., J. Medina-Pestana   +8 more
doaj   +1 more source

Study Protocol for Better Evidence for Selecting Transplant Fluids (BEST-Fluids): a pragmatic, registry-based, multi-center, double-blind, randomized controlled trial evaluating the effect of intravenous fluid therapy with Plasma-Lyte 148 versus 0.9% saline on delayed graft function in deceased donor kidney transplantation

Trials, 2020
Background Delayed graft function, the requirement for dialysis due to poor kidney function post-transplant, is a frequent complication of deceased donor kidney transplantation and is associated with inferior outcomes and higher costs. Intravenous fluids
Michael G. Collins, Magid A. Fahim, Elaine M. Pascoe, Kathryn B. Dansie, Carmel M. Hawley, Philip A. Clayton, Kirsten Howard, David W. Johnson, Colin J. McArthur, Rachael C. McConnochie, Peter F. Mount, Donna Reidlinger, Laura Robison, Julie Varghese, Liza A. Vergara, Laurence Weinberg, Steven J. Chadban, for the BEST-Fluids Investigators and the Australasian Kidney Trials Network   +17 more
doaj   +1 more source

Risk factors for delayed kidney graft function from a deseased donor

Трансплантология (Москва), 2022
Aim. To determine statistically significant risk factors for delayed renal graft function. To assess the impact of delayed kidney graft function on the development of other complications, graft and recipient survival.Material and methods.
A. V. Shabunin, P. A. Drozdov, I. V. Nesterenko, D. A. Makeev, O. S. Zhuravel, S. A. Astapovich   +5 more
doaj   +1 more source

Deceased donor renal transplantation at army hospital research and referral: Our experience

Indian Journal of Urology, 2013
Context: In India, there are a large number of end-stage renal disease (ESRD) patients waiting for renal transplant. Deceased donor organ transplantation (DDOT) is the possible solution to bridge the disparity between organ supply and demand. The concept
Yogesh Kumar Swami, Dharam Vir Singh, Sanjay K Gupta, Aditya A Pradhan, Yajvender P. S. Rana, Sandeep Harkar, M Shafi Wani   +6 more
doaj   +1 more source

Early experiments with hypothermic oxygenated machine perfusion of kidney grafts from extended criteria donors

Вестник трансплантологии и искусственных органов, 2022
Objective: to evaluate the safety and efficacy of hypothermic oxygenated machine perfusion (HOPE) for kidney grafts obtained from expanded criteria donors (ECD).Materials and methods.
A. V. Shabunin, M. G. Minina, P. V. Drozdov, I. V. Nesterenko, D. A. Makeev, O. S. Zhuravel, L. R. Karapetyan, S. A. Astapovich   +7 more
doaj   +1 more source

Clinical outcomes prediction in kidney transplantation by use of biomarkers from hypothermic machine perfusion [PDF]

International Brazilian Journal of Urology
Purpose The clinical outcomes of kidney transplantation from deceased donors have seen significant improvements with the use of machine perfusion (MP), now a standard practice in transplant centers. However, the use of perfusate biomarkers for assessing
Ricardo Ribas de Almeida Leite, Maurilo Leite Jr, Marcelo Einicker-Lamas, Rafael Hospodar Felippe Valverde, Luiz Carlos Duarte Miranda, Alberto Schanaider   +5 more
doaj   +1 more source

A molecular signature for delayed graft function [PDF]

Aging Cell, 2018
AbstractChronic kidney disease and associated comorbidities (diabetes, cardiovascular diseases) manifest with an accelerated ageing phenotype, leading ultimately to organ failure and renal replacement therapy. This process can be modulated by epigenetic and environmental factors which promote loss of physiological function and resilience to stress ...
Dagmara McGuinness, Suhaib Mohammed, Laura Monaghan, Paul A. Wilson, David B. Kingsmore, Oliver Shapter, Karen S. Stevenson, Shana M. Coley, Luke Devey, Robert B. Kirkpatrick, Paul G. Shiels   +10 more
openaire   +3 more sources

Delayed Graft Function in the Kidney Transplant [PDF]

American Journal of Transplantation, 2011
Acute kidney injury occurs with kidney transplantation and too frequently progresses to the clinical diagnosis of delayed graft function (DGF). Poor kidney function in the first week of graft life is detrimental to the longevity of the allograft. Challenges to understand the root cause of DGF include several pathologic contributors derived from the ...
A, Siedlecki, W, Irish, D C, Brennan
openaire   +2 more sources

Delayed Graft Function and the Risk for Death with a Functioning Graft [PDF]

Journal of the American Society of Nephrology, 2010
Delayed graft function (DGF) associates with an increased risk for graft failure, but its link with death with graft function (DWGF) is unknown. We used the US Renal Data System to assemble a cohort of all first, adult, deceased-donor kidney transplant recipients from January 1, 1998, through December 31, 2004.
Shruti N, Tapiawala, Kathryn J, Tinckam, Carl J, Cardella, Jeffrey, Schiff, Daniel C, Cattran, Edward H, Cole, S Joseph, Kim   +6 more
openaire   +2 more sources

Delayed graft function in renal transplantation

Current Opinion in Critical Care, 2004
Delayed graft function is an important determinant of patient and graft survival. A complex of pathologic mechanisms intervenes in the pathophysiology of this outcome. This paper reviews the main processes involved in delayed graft function as they relate to five chronologically related stages: donor tissue quality, brain death and related stress ...
Patrick, Peeters, Wim, Terryn, Raymond, Vanholder, Norbert, Lameire   +3 more
openaire   +4 more sources