Results 51 to 60 of about 113,009 (309)

Risk factors and consequences of delayed graft function

Saudi Journal of Kidney Diseases and Transplantation, 2013
The impact of delayed graft function (DGF) on the outcome of renal transplantation remains controversial. We analyzed the risk factors for DGF and its impact on graft and patient survival.
Mondher Ounissi, Mejda Cherif, Taieb Ben Abdallah, Mongi Bacha, Hafedh Hedri, Ezzedine Abderrahim, Rym Goucha, Adel Kheder, Riadh Ben Slama, Amine Derouiche, Mohamed Chebil, Rafika Bardi, Imen Sfar, Yosr Gorgi   +13 more
doaj   +1 more source

Hematopoietic (stem) cells—The elixir of life?

FEBS Letters, EarlyView.
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo, Jonah Anderson, Emilie Dinh Vedrenne, Noël Yeh Martín, Jette Lengefeld   +4 more
wiley   +1 more source

An Analysis of Early Renal Transplant Protocol Biopsies - the High Incidence of Subclinical Tubulitis [PDF]

, 2001
To investigate the possibility that we have been underestimating the true incidence of acute rejection, we began to perform protocol biopsies after kidney transplantation. This analysis looks at the one-week biopsies. Between March 1 and October 1, 1999,
Burdick, D'Ardenne, Hanas, Kjellstrand, Racusen, Randhawa, Rush, Rush, Rush, Saad, Seron, Shapiro, Shapiro, Shapiro, Shapiro, Solez, Starzl   +16 more
core   +1 more source

Kidney Transplant Outcomes after Prolonged Delayed Graft Function

Journal of Clinical Medicine, 2022
Background: The protracted recovery of renal function may be an actionable marker of post-transplant adverse events, but a paucity of data are available to determine if the duration of graft recovery serves to stratify risk. Materials and Methods: Single-center data of adult-isolated deceased-donor kidney transplant (KTX) recipients between 1 July 2015
Cullan V. Donnelly, Maria Keller, Liise Kayler   +2 more
openaire   +2 more sources

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Prolonged graft survival in older recipient mice is determined by impaired effector T-cell but intact regulatory T-cell responses. [PDF]

PLoS ONE, 2010
Elderly organ transplant recipients represent a fast growing segment of patients on the waiting list. We examined age-dependent CD4(+) T-cell functions in a wild-type (WT) and a transgenic mouse transplant model and analyzed the suppressive function of ...
Christian Denecke, Damanpreet Singh Bedi, Xupeng Ge, Irene Kyung-Eun Kim, Anke Jurisch, Anne Weiland, Antje Habicht, Xian C Li, Stefan G Tullius   +8 more
doaj   +1 more source

Tacrolimus in pediatric renal transplantation [PDF]

, 1996
Tacrolimus was used as the primary immunosuppressive agent in 69 pediatric renal transplantations between December 17, 1989, and June 30, 1995. Children undergoing concomitant or prior liver and/or intestinal transplantation were excluded from analysis ...
Ellis, D, Fung, JJ, Gilboa, N, Gritsch, HA, Hakala, TR, Irish, W, Jordan, ML, Lombardozzi-Lane, S, Scantlebury, VP, Shapiro, R, Simmons, RL, Starzl, TE, Vivas, C   +12 more
core   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

A prospective, randomized trial of tacrolimus/prednisone versus tacrolimus/prednisone/mycophenolate mofetil in renal transplant recipients [PDF]

, 1999
Background. Between September 20, 1995 and September 20, 1997, 208 adult patients undergoing renal transplantation were randomized to receive tacrolimus/prednisone (n=106) or tacrolimus/prednisone/mycophenolate mofetil (n=102), with the goal of reducing ...
Carlos Vivas, Czer, Gjertson, H. Albin Gritsch, J. Wallis Marsh, James Johnston, Japanese, Jerry McCauley, John J. Fung, Jordan, Kaplan, Mantel, Mark L. Jordan, Mayer, Miller, Murie, Nashan, Parmjeet Randhawa, Pirsch, Robert Naraghi, Ron Shapiro, Roth, Roza, Shapiro, Shapiro, Shapiro, Shapiro, Starzl, Thomas E. Starzl, Thomas R. Hakala, Toyoda, Velma P. Scantlebury, Vincenti, Vivas, William Irish, Zucker   +35 more
core   +1 more source

BuMPy road of delayed graft function

American Journal of Physiology-Renal Physiology, 2012
delayed graft function (DGF) occurs in 20–30% of renal transplants and contributes significantly to the gradual loss of grafts through accelerated development of chronic allograft dysfunction. Members of the transforming growth factor-β (TGF-β) family are incriminated as the major driving force for developing fibrosis.
openaire   +3 more sources