Results 111 to 120 of about 250,782 (299)

Aniracetam does not improve working memory in neurologically healthy pigeons.

PLoS ONE, 2019
Understanding the effects of cognitive enhancing drugs is an important area of research. Much of the research, however, has focused on restoring memory following some sort of disruption to the brain, such as damage or injections of scopolamine ...
Hannah Phillips, Arlene McDowell, Birgitte S Mielby, Ian G Tucker, Michael Colombo   +4 more
doaj   +1 more source

Theta oscillation and neuronal activity in rat hippocampus areinvolved in temporal discrimination of time in seconds

Frontiers in Systems Neuroscience, 2015
The discovery of time cells revealed that the rodent hippocampus has information of time.Previous studies have suggested that a role of hippocampal time cells is to integratetemporally segregated events into a sequence using working memory with time ...
Tomoaki eNakazono, Tomoaki eNakazono, Tomomi eSano, Susumu eTakahashi, Yoshio eSakurai, Yoshio eSakurai   +5 more
doaj   +1 more source

Fluid Biomarkers of Disease Burden and Cognitive Dysfunction in Progressive Supranuclear Palsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Identifying objective biomarkers for progressive supranuclear palsy (PSP) is crucial to improving diagnosis and establishing clinical trial and treatment endpoints. This study evaluated fluid biomarkers in PSP versus controls and their associations with regional 18F‐PI‐2620 tau‐PET, clinical, and cognitive outcomes.
Roxane Dilcher, Charles B. Malpas, Stuart J. McDonald, William T. O’Brien, Craig Despott, Kelly L. Bertram, Matthew P. Pase, Lukas Frontzkowski, Meng Law, Terence J. O’Brien, Lucy Vivash   +10 more
wiley   +1 more source

The effect of real-world personal familiarity on the speed of face information processing.

PLoS ONE, 2007
BackgroundPrevious studies have explored the effects of familiarity on various kinds of visual face judgments, yet the role of familiarity in face processing is not fully understood.
Benjamin Balas, David Cox, Erin Conwell
doaj   +1 more source

EEG and autonomic responses during performance of matching and non-matching to sample working memory tasks with emotional content.

Frontiers in Behavioral Neuroscience, 2011
Working memory (WM) is a neural system responsible for the temporary storage of information and its utilization in problem solving. The central executive is theorized as the controller of storage functions that support WM. Neurophysiological data suggest
Ana eGarcia, Carlos Enrique eUribe, Maria Clotilde eTavares, Carlos eTomaz   +3 more
doaj   +1 more source

Inference in Complex Systems Using Multi-Phase MCMC Sampling With Gradient Matching Burn-in [PDF]

, 2017
We propose a novel method for parameter inference that builds on the current research in gradient matching surrogate likelihood spaces. Adopting a three phase technique, we demonstrate that it is possible to obtain parameter estimates of limited bias ...
Husmeier, Dirk, Lazarus, Alan, Papamarkou, Theodore   +2 more
core  

Baseline Regional Cholinergic Denervation Predicts Cognitive Trajectories in Moderate Parkinson Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Cognitive decline is a disabling and variable feature of Parkinson disease (PD). While cholinergic system degeneration is linked to cognitive impairments in PD, most prior research reported cross‐sectional associations. We aimed to fill this gap by investigating whether baseline regional cerebral vesicular acetylcholine transporter ...
Taylor Brown, Giulia Carli, Prabesh Kanel, Stiven Roytman, Jaimie Barr, Nicolaas I. Bohnen, Roger L. Albin   +6 more
wiley   +1 more source

Analysis of the Hemoglobin Level Drop in Patients with Hip Fracture After Admission

Acta Clinica Croatica, 2017
The studies that evaluated blood loss during hip surgery found a relatively small loss that does not explain the large hemoglobin drop postoperatively. The aim of this study was to determine the fall in hemoglobin level after admission and rehydration in
Viktor Kamiloski, Katerina Kasapinova
doaj   +1 more source

A Prospective Study of Individuals at Risk of Multiple Sclerosis Informs the Design of Primary Prevention Studies

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective In multiple sclerosis, the optimal time for deploying a therapeutic intervention is before the central nervous system is damaged; given the success of trials treating the earliest stage of MS, the radiologically isolated syndrome, developing primary prevention strategies is an important next challenge.
Amy W. Laitinen, Ceren Tozlu, Tina Roostaei, Fatoumata Diallo, Kaho Onomichi, Jiyeon Son, Zongqi Xia, Philip L. De Jager   +7 more
wiley   +1 more source

Developmental and Epileptic Encephalopathy due to Biallelic Pathogenic Variants in PIGM

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective PIGM encodes a critical enzyme in the glycosylphosphatidylinositol (GPI)‐anchor biosynthesis pathway. While promoter‐region mutations in PIGM have been associated with a relatively mild phenotype characterized by portal vein thrombosis and absence seizures, recent evidence suggests that coding‐region mutations result in a more severe
Júlia Sala‐Coromina, Anna Marcé‐Grau, Barbara Masotto, Marta Codina, Lamia BenJemaa, Yasmina Elaribi, Mónica Martinez‐Gallo, Roger Colobran, Angel Sanchez‐Montañez, Irene Valenzuela, Yoshiko Murakami, Alfons Macaya   +11 more
wiley   +1 more source