Results 51 to 60 of about 250,782 (299)

Novel Genetic Risk Factor Identified for L‐Asparaginase‐Induced Pancreatitis in Pediatric Patients With Cancer

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background L‐asparaginase is a critical component in treatment protocols for pediatric acute lymphoblastic leukemia. Acute pancreatitis reactions can necessitate delays and, in some cases, discontinuation of L‐asparaginase, which compromises outcomes.
Edward J. Raack, Wan‐Chun Chang, Miguel Cordova‐Delgado, Spencer J. Anderson, Jessica N. Trueman, Erika N. Scott, Catrina M. Loucks, Shahrad R. Rassekh, Gabriella S. S. Groeneweg, Michelle Higginson, Kathy Li, Fudan Miao, Derek Yau, Donna Johnston, Mounira Ibrahim, Maja Krajinovic, Thai Hoa Tran, Jessica Tewfik, Jean‐François Bussières, Thaïna‐Rafi Jean‐Baptiste, Denis Lebel, Lucie Pecheux, Bina Gyawali, Gregory Guilcher, Gesche Riabowol, Geert ’t Jong, Michelle Staub, Geoff Cuvelier, Kathleen Felton, Sara Khalaj, Michael Rieder, Awatif Abuzgaia, Tamorah Lewis, Himal Ghimire, Paul Nathan, Kerry Goralski, Ketan Kulkarni, Zara Forbrigger, Colin J. D. Ross, Bruce C. Carleton   +39 more
wiley   +1 more source

Working-memory load decoding model inspired by brain cognition based on cross-frequency coupling

Brain Research Bulletin
Working memory, a fundamental cognitive function of the brain, necessitates the evaluation of cognitive load intensity due to limited cognitive resources.
Jing Zhang, Tingyi Tan, Yuhao Jiang, Congming Tan, Liangliang Hu, Daowen Xiong, Yikang Ding, Guowei Huang, Junjie Qin, Yin Tian   +9 more
doaj   +1 more source

Strain differences between C57Bl/6 and DBA/2 mice (Mus musculus) in delayed matching and nonmatching-to-position tasks: impact of sample responses and delay intervals [PDF]

PeerJ
Background Spatial working memory is commonly assessed in rodents using delayed matching-to-position (DMTP) and delayed nonmatching-to-position (DNMTP) tasks.
Kazuhiro Goto
doaj   +2 more sources

Basal ganglia and memory retrieval during delayed match-to-sample and non-match-to-sample tasks [PDF]

BMC Neuroscience, 2009
Top-down guidance of visual search requires the ability tobias the processing of visual features towards the charac-teristics of the desired object. Whatever form they maytake, these characteristics (that we will call here a templateof the object) have to be transferred from memory to thevisual cortical areas, either from long-term memory orworking ...
Hamker Fred, Vitay Julien
openaire   +2 more sources

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Sensory capability and information integration independently explain the cognitive status of healthy older adults

Scientific Reports, 2020
While there is evidence that sensory processing and multisensory integration change with age, links between these alterations and their relation to cognitive status remain unclear.
Jonas Misselhorn, Florian Göschl, Focko L. Higgen, Friedhelm C. Hummel, Christian Gerloff, Andreas K. Engel   +5 more
doaj   +1 more source

DELAYED REINFORCEMENT AND DELAYED CHOICE IN SYMBOLIC MATCHING TO SAMPLE: EFFECTS ON STIMULUS DISCRIMINABILITY [PDF]

Journal of the Experimental Analysis of Behavior, 1986
Six pigeons were trained to peck a red side key when the brighter of two white lights (S1) had been presented on the center key, and to peck a green side key when the dimmer of two white lights (S2) had been presented on the center key. Equal frequencies of reinforcers were provided for the two types of correct choice.
D, McCarthy, M, Davison
openaire   +2 more sources

Ideal timing to transfer from an acute care hospital to an interdisciplinary inpatient rehabilitation program following a stroke: an exploratory study [PDF]

, 2006
Affiliation: Dany Gagnon & Sylvie Nadeau: École de réadaptation, Faculté de médecine, Université de Montréal & Centre de recherche interdisciplinaire en réadaptation, Institut de réadaptation de MontréalBACKGROUND:Timely accessibility to organized ...
Dany Gagnon, Sylvie Nadeau, Vincent Tam, Canadaian Heart and Stroke Surveillance System, D Gagnon, E Roth, P Langhorne, NE Mayo, S Shah, ME Brandstater, S Paolucci, S Paolucci, BS Tur, MV Johnston, A Suputtitada, TB Wyller, C Weimar, AW Heinemann, C Kevorkian, A Deutsch, M Mussico, K Salter, Center for Functional Assessment Research, ME Cohen, KA Brock, US Department of Health and Human Services, K Brock, L Brosseau, S Giaquinto, D Schlegel, R Keith, P Duncan, S Finger, MH Milot, JB Green, G Nolfe, M Inouye, A Wolfson, C Partridge, A Slade, H Ghoge, K Ottenbacher   +41 more
core   +3 more sources

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

EFFECT OF DELAY‐INTERVAL STIMULI ON DELAYED SYMBOLIC MATCHING TO SAMPLE IN THE PIGEON [PDF]

Journal of the Experimental Analysis of Behavior, 1981
In Experiment 1, food‐deprived pigeons received delayed symbolic matching to sample training in a darkened Skinner box. Trials began with the illumination of the grain feeder lamp (no food sample), or illumination of this lamp, accompanied by the raising of the feeder tray (food sample).
D M, Wilkie, R J, Summers, M L, Spetch
openaire   +2 more sources