Results 71 to 80 of about 250,782 (299)

Retrospective versus prospective processes in delayed matching to sample [PDF]

Bulletin of the Psychonomic Society, 1984
Current views of delayed matching-to-sample (DMTS) performance in pigeons postulate the active maintenance (rehearsal) of a representation of the sample stimulus during the delay in­ terval. Honig and Wasserman (1981) termed this type of processing retrospective.
Thomas B. Stonebraker, Mark Rilling
openaire   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Davunetide sex-dependently boosts memory in prodromal Alzheimer’s disease

Translational Psychiatry
Background The tauopathy inhibitor, davunetide shows sex-dependent efficacy in women suffering from progressive supranuclear palsy. Extending these findings to prodromal Alzheimer’s disease, we submitted a double-blind, placebo-controlled, 12 weeks/16 ...
Illana Gozes, Jason Blatt, Alexandra Lobyntseva   +2 more
doaj   +1 more source

Perirhinal Cortex Neuronal Activity is Actively Related to Working Memory in the Macaque

Neural Plasticity, 2002
Lesion studies suggest that the perirhinai cortex plays a role in object recognition memory. To analyze its role, we recorded the activity of single neurons in the perirhinal cortex in a rhesus monkey (Macaca mulatta) performing a delayed matching-to ...
Christian Hölscher, Edmund T. Rolls
doaj   +1 more source

Severity of specific language impairment predicts delayed development in number skills [PDF]

, 2013
The extent to which mathematical development is dependent upon language is controversial. This longitudinal study investigates the role of language ability in children's development of number skills.
Conti-Ramsden, Gina, Durkin, Kevin, Mok, Pearl   +2 more
core   +2 more sources

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

The protocol for assessing olfactory working memory capacity in mice

Brain and Behavior, 2022
Background Working memory capacity (WMC) is the ability to maintain information over a few seconds. Although it has been extensively studied in healthy subjects and neuropsychiatric patients, few tasks have been developed to measure such changes in ...
Li‐Xin Jiang, Geng‐Di Huang, Hua‐Li Wang, Chen Zhang, Xin Yu   +4 more
doaj   +1 more source

NKCC1: A key regulator of glioblastoma progression

Molecular Oncology, EarlyView.
Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen, Diana Freitag, Madlen Haase, Christian Senft, Falko Schwarz, Silke Keiner   +5 more
wiley   +1 more source

Emission of photon echoes in a strongly scattering medium

, 2011
We observe the two- and three-pulse photon echo emission from a scattering powder, obtained by grinding a Pr$^{3+}$:Y$_2$SiO$_5$ rare earth doped single crystal. We show that the collective emission is coherently constructed over several grains.
A. Ferrier, Abella, Baudrier-Raybaut, Cao, Colice, de Boer, de Riedmatten, F. Beaudoux, Feng, Gorju, Ito, J.-L. Le Gouët, Kravtsov, Kurnit, Macfarlane, Markushev, Mossberg, O. Guillot-Noël, Ph. Goldner, T. Chanelière, Tittel, Van Albada, Vanneste, Wellens, Wellens, Wen, Wiersma, Wolf, Zhi   +28 more
core   +3 more sources

Antibiofilm activity of a chionodracine‐derived peptide by NMR‐based metabolomics of cell‐free supernatant of Acinetobacter baumannii clinical strains

FEBS Open Bio, EarlyView.
KHS‐Cnd peptide is able to impair biofilm formation and disaggregate mature biofilms in Acinetobacter baumannii clinical isolates. Differences in extracellular metabolites reflect changes in biofilm metabolism due to KHS‐Cnd treatment. Among the differentially represented extracellular metabolites upon KHS‐Cnd treatment, the significantly altered ...
Fernando Porcelli, Enrico Landi, Francesco Maiurano, Irene Paris, Rosanna Papa, Marco Artini, Laura Selan, Stefano Borocci, Francesco Buonocore, Esther Imperlini   +9 more
wiley   +1 more source