Results 121 to 130 of about 4,738 (174)

Artificial intelligence-based screening of phytochemicals for targeted cancer therapy. [PDF]

open access: yesNat Prod Bioprospect
Santiago LR   +14 more
europepmc   +1 more source

Myrcene‐Based Tailored Co‐Polymers as Active Pharmaceutical Excipients: Bio‐Based Solutions for Mucoadhesive Excipients

open access: yesAdvanced Functional Materials, EarlyView.
Mucoadhesive amphiphilic block and statistical copolymers were synthesized via Reversible Addition–Fragmentation Chain Transfer polymerization from bio‐sourced myrcene and polyethylene glycol methacrylate. The resulting polymers exhibit narrow molar‐mass distributions, high regioselectivity, well‐defined microstructures, and tend to self‐assemble into ...
David Gintsburg   +9 more
wiley   +1 more source

Engineering MnNiPx Cathode via Dual Role of Mn: Simultaneous Enhancement of Activity and Intermittent Operation Durability

open access: yesAdvanced Functional Materials, EarlyView.
Engineering MnNiPx cathodes through the dual role of Mn simultaneously improves hydrogen evolution reaction activity and intermittent‐operation durability. Mn preferentially oxidizes to protect Ni–P sites from irreversible oxidation, while metallic Mn incorporation enhances the HER kinetics of Ni–P active layer.
Ik‐Sun Kim   +16 more
wiley   +1 more source

Shape Memory Microneedle to Prevent Risks of Reproductive Hormone Therapy by Switching Sustained to Burst Release Under a Single Transdermal Insertion

open access: yesAdvanced Functional Materials, EarlyView.
A shape‐memory microneedle system enables reproductive hormone therapy through a single transdermal insertion. The X‐shaped device sustains follicle‐stimulating hormone release for three days, and mild heating restores the O shape to trigger burst human chorionic gonadotropin release.
Sungwoo Cho   +8 more
wiley   +1 more source

Interstitium‐Mimicking Porous Alveolar Membranes Enable Physiologic Aerosol Transport and Distinct Acute‐Chronic Lung Injury Responses

open access: yesAdvanced Functional Materials, EarlyView.
An interstitium‐mimicking membrane combines three‐dimensional alveolar geometry, high pore interconnectivity, and mechanical compliance to overcome transport limitations of conventional lung‐on‐chip barriers. The resulting platform supports physiologic aerosol transport, quantitative analysis of cross‐barrier particle movement, and reveals divergent ...
Jae‐Won Choi   +11 more
wiley   +1 more source

Chemical Maturation Controls Bioavailability of Fetuin‐A‐Mineral Complexes in Biomineralization

open access: yesAdvanced Functional Materials, EarlyView.
The role of Fetuin‐A‐mineral complexes in matrix mineralization is unclear. Here, Fetuin‐A‐mineral complexes were found to exist in functionally distinct states that determine mineral bioavailability: chemically labile calciprotein monomers directly mineralize collagen fibrils, while chemically matured primary calciprotein particles require cellular ...
Judith M. Schaart   +8 more
wiley   +1 more source

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