Results 161 to 170 of about 23,104 (266)

Programming Light‐Driven Surface Topographies in Liquid Crystal Elastomers for Potential Biomedical Applications Through Combined Experiments and Simulations

open access: yesAdvanced Materials Technologies, EarlyView.
A combined experimental and simulation study of light‐responsive liquid crystal elastomer surfaces operating under physiological conditions is reported, demonstrating programmable and highly spatially controlled topography formation through bottom‐side photomask exposure. Our study establishes a foundation for dynamic, light‐responsive biosurfaces with
Ruth M. C. Verbroekken   +4 more
wiley   +1 more source

AI‐Powered Framework for Evaluating Drug Efficacy for Three‐Dimensional In Vitro Cancer Models in Robot‐Assisted Production

open access: yesAdvanced Robotics Research, EarlyView.
An AI‐powered, robot‐assisted framework automatically produces, images, and analyzes 3D tumor spheroids to evaluate drug efficacy. Integrated modules handle spheroid formation, live/dead staining, brightfield imaging, and automated image analysis, including spheroid segmentation, viability and metrics to assess the drug treatment efficacy. The workflow
Dalia Mahdy   +13 more
wiley   +1 more source

Intravital Multimodal Imaging of Human Cortical Organoid Transplantation in a Mouse Model of Chronic Stroke

open access: yesAdvanced Science, EarlyView.
A multimodal intravital imaging platform enables longitudinal tracking of human cortical organoids transplanted into chronic stroke lesions. By combining surgical microscopy, MRI, bioluminescence imaging, and two‐photon fluorescence microscopy, the platform captures graft placement, viability dynamics, and cellular‐scale morphology in vivo, offering a ...
Jinghui Wang   +12 more
wiley   +1 more source

Solid Harmonic Wavelet Bispectrum for Image Analysis

open access: yesAdvanced Science, EarlyView.
The Solid Harmonic Wavelet Bispectrum (SHWB), a rotation‐ and translation‐invariant descriptor that captures higher‐order (phase) correlations in signals, is introduced. Combining wavelet scattering, bispectral analysis, and group theory, SHWB achieves interpretable, data‐efficient representations and demonstrates competitive performance across texture,
Alex Brown   +3 more
wiley   +1 more source

Cross Kingdom Metabolic Engineering Paradigm Elevating Sustainable Protein Production

open access: yesAdvanced Science, EarlyView.
ABSTRACT Confronting the dual crisis of escalating global protein demand and unsustainable agriculture necessitates transformative solutions. Here, we pioneer evolutionary insights from maize nitrogen optimization via asparagine synthetase (ASNS) to rewire metabolism in Pichia pastoris.
Yuanyuan Du   +4 more
wiley   +1 more source

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