Results 41 to 50 of about 53,293 (309)
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
The Polish Regional Labour Market Welfare Indicator And Its Links To Other Well-being Measures
We propose and construct an indicator of labour market well-being in Poland for the year 2013. The indicator is positively related to the degree of civilizational welfare, social welfare, material welfare and psychological wellbeing in Poland.
Marek Ręklewski, Maciej Ryczkowski
doaj +1 more source
The sky's the limit? Establishing a legal delimitation of airspace and outer space [PDF]
The debate over the legal delimitation between air and space has been argued for over half a century. In representing the positions of those concerned one can show the need for a boundary between airspace and outer space.
Monahan, Rhys
core
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source
Species delimitation and global biosecurity
Species delimitation directly impacts on global biosecurity. It is a critical element in the decisions made by national governments in regard to the flow of trade and to the biosecurity measures imposed to protect countries from the threat of invasive ...
De Barro, PJ +7 more
core +1 more source
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
Malapportionment in Mongolian elections: Does institutional structure matter?
This article examines malapportionment in Mongolia from the introduction of a unicameral parliament in 1992 to the parliamentary elections in 2016. We especially address the question whether the level of malapportionment was significantly influenced by ...
Pavel Maškarinec
doaj +1 more source
Issues and problems in Mediterranean maritime boundary delimitation : a geographical analysis. [PDF]
In 2 volsAvailable from British Library Document Supply Centre- DSC:DX179488 / BLDSC - British Library Document Supply CentreSIGLEGBUnited ...
Langford, Stephen Roy, Langford, S.R
core
Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski +10 more
wiley +1 more source
ENERGY ISSUES AS THE TRIGGER OF FORMATION OF AN INTERNATIONAL REGIME OF THE CASPIAN SEA
The research object of the article is a development of the international regime of the Caspian Sea after the collapse of the Soviet Union in 1991 and increase in the number of the Caspian Littoral States, which transformed the former “closed” Soviet ...
I. S. Rozhkov
doaj +1 more source

