Results 41 to 50 of about 194,176 (361)
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
The Polish Regional Labour Market Welfare Indicator And Its Links To Other Well-being Measures
Comparative Economic Research, 2016 We propose and construct an indicator of labour market well-being in Poland for the year 2013. The indicator is positively related to the degree of civilizational welfare, social welfare, material welfare and psychological wellbeing in Poland.
Marek Ręklewski, Maciej Ryczkowski
doaj +1 more source
Maritime Delimitation in the Black Sea (Romania v. Ukraine) [PDF]
, 2009 The complex relationship between psychic structures, social norms, and aesthetic representations is a challenge for every analysis of the historical manifestations of human desire.
Lathrop, Coalter G.
core +1 more source
Molecular Oncology, EarlyView.Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Malapportionment in Mongolian elections: Does institutional structure matter?
Cogent Social Sciences, 2023 This article examines malapportionment in Mongolia from the introduction of a unicameral parliament in 1992 to the parliamentary elections in 2016. We especially address the question whether the level of malapportionment was significantly influenced by ...
Pavel Maškarinec
doaj +1 more source
Molecular Oncology, EarlyView.We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source
Maps, fields, and boundary cairns: demarcation and resistance in colonial Cyprus [PDF]
, 2002 An important component of the administration and control of a colony by an external power was the demarcation and classification of the land and its people.
Given, M.
core +1 more source
Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
An Institutionalist Outlook On The Origins Of Property From The Perspective Of Transaction Costs [PDF]
Annals of the University of Oradea: Economic Science, 2008 In new institutionalists’ analysis, the transaction costs are essential in explaining the origin of private property; however, this aspect is not that obvious in old institutionalists’ works. But even if they did not emphasize on this issue, they created
Pohoata Ion, Iacobuta Andreea-Oana
doaj