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Datura Delirium

Clinical Neuropharmacology, 1992
Poisoning with tropine alkaloids from cultivated plants and pharmaceuticals is an uncommon cause of delirium and coma. We report a patient with a toxic delirium following ingestion of the tropine alkaloid-containing root of Datura innoxia. Thin-layer chromatography and gas chromatography/mass spectrometry confirmed the presence of atropine and ...
J P, Hanna   +2 more
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Delirium in the Elderly

Clinics in Geriatric Medicine, 2018
Delirium is defined as an acute disturbance in attention and cognition, with significant associated morbidity and mortality. This article discusses the basic epidemiology of delirium and approaches to diagnosing, assessing, and working up patients for delirium.
Tammy T, Hshieh   +2 more
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Delirium in the Elderly

Journal of Geriatric Psychiatry and Neurology, 1988
Delirium is an organic psychiatric syndrome characterized by acute onset and impairment in cognition, perception, and behavior. The most common and serious mental disorder in old age, delirium heralds death in about 25% of afflicted elderly patients.
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Aripiprazole and Delirium

Annals of Clinical Psychiatry, 2006
Delirium is a common condition frequently seen in consultation-liaison psychiatry. It is especially common among medically compromised patients and is an indicator of the severity of the medical illness. In addition, it is associated with a higher morbidity, mortality or longer hospitalization. Traditionally, haloperidol has been used to treat delirium-
Adekola O, Alao, Lindsay, Moskowitz
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DELIRIUM IN THE ELDERLY

Psychiatric Clinics of North America, 1997
Delirium is a state of disturbed consciousness and attention and cognition or perception, which develops acutely, fluctuates during the course of the day, and is attributable to a physical disorder. This syndrome is the focus of increasing attention in light of emerging evidence of its enormous impact in human suffering as well as patient care costs ...
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Antipsychotics for delirium

2006
Delirium occurs in up to 30% of hospitalised patients and is associated with prolonged hospital stay and increased morbidity and mortality. Recently published reports have suggested that the standard drug for delirium, haloperidol, a typical antipsychotic that may cause adverse extrapyramidal symptoms among patients, may be replaced by atypical ...
E, Lonergan   +3 more
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ICU Delirium

Neurologic Clinics
Delirium is not a harmless transient event during ICU hospitalization; rather, it is a severe complication of critical illness associated with increased mortality, morbidity, and persistent disability. Despite being recognized for decades, it remains underdiagnosed. Employing validated tools for detection helps reduce missed cases.
Amra, Sakusic, Alejandro A, Rabinstein
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Pathophysiology of Delirium

Journal of Geriatric Psychiatry and Neurology, 1998
Hypotheses about the pathophysiology of delirium are speculative and largely based on animal research. According to the neurotransmitter hypothesis, decreased oxidative metabolism in the brain causes cerebral dysfunction due to abnormalities of various neurotransmitter systems.
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Delirium

Geriatric Nursing, 1987
G E, Gomez, E A, Gomez
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The Concept of Delirium

Dementia and Geriatric Cognitive Disorders, 1999
The concept of delirium has a long and confusing history. This article outlines the development of ideas relating to core features of the syndrome: disturbance of consciousness, disturbance of cognition, its course and its external causation. The modern concept of delirium, and the diagnostic criteria found in current classifications are based upon a ...
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