Results 91 to 100 of about 1,852,348 (320)

Comprehensive Profiling of N6‐methyladnosine (m6A) Readouts Reveals Novel m6A Readers That Regulate Human Embryonic Stem Cell Differentiation

Advanced Science, EarlyView.
This research deciphers the m6A transcriptome by profiling its sites and functional readout effects: from mRNA stability, translation to alternative splicing, across five different cell types. Machine learning model identifies novel m6A‐binding proteins DDX6 and FXR2 and novel m6A reader proteins FUBP3 and L1TD1.
Zhou Huang, Rucong Liu, Zibaguli Wubulikasimu, Wanqing Zhao, Jiaqi Huang, Jiaxuan Wang, Tianyuan Zhang, Rui Fan, Wei Kong, Qinghua Cui, Yang Li, Yuan Zhou   +11 more
wiley   +1 more source

Relationship between the anxiety of labor companion and labor satisfaction among laboring women

Scientific Reports
The presence of a known labor companion was shown to improve childbirth satisfaction. However, a companion’s anxiety might affect the satisfaction of laboring women.
Amirreza Nasirzadeh, Fatemeh Mohammadzadeh, Sedighesadat Kazeminia, Arezoo Davarinia Motlagh Quchan, Sareh Dashti, Narjes Bahri   +5 more
doaj   +1 more source

HRS Degradation‐Induced Nicotinamide Deficiency in Placental Extracellular Vesicles Triggers Preeclampsia by Disrupting Maternal‐Fetal Immune Homeostasis

Advanced Science, EarlyView.
This study shows that lower NAM levels in PE‐derived pEVs correlate with disease severity. NAM‐deficient pEVs reduce Th1 and Th17 inhibition, leading to PE‐like symptoms. NAM in pEVs inhibits Th1 via SIRT1 and Th17 via macrophages. Reduced NAM in PE‐EVs is due to decreased HRS expression in trophoblasts, resulting from elevated HSP27.
Haiyi Fei, Yuhan Lin, Xiu Liu, Xiaohong Zhu, Xiaowen Lu, Zhan Shi, Fan Jia, Shiqian Xu, Ling Fang, Lingling Jiang, Songying Zhang   +10 more
wiley   +1 more source

Transversus abdominis plane blocks; a national survey of techniques used by UK obstetric anaesthetists [PDF]

, 2011
No abstract ...
Kearns, R.J., Young, S.J.
core   +1 more source

Metabolic Reprogramming Driven by Trophoblasts and Decidual XCR1+PMN‐MDSC Crosstalk Controls Adverse Outcomes Associated With Advanced Maternal Age

Advanced Science, EarlyView.
The interaction between trophoblasts and decidual polymorphonuclear myeloid‐derived suppressor cells (dPMN‐MDSCs) via the XCL1–XCR1 axis is crucial for fetal development during the third trimester. Disruption of this axis impairs FOXO1 activity and causes metabolic imbalance in dPMN‐MDSCs, contributing to adverse outcomes associated with advanced ...
Meiqi Chen, Yuxiong Guo, Qing Zhao, Jingping Liu, Shuyi Kuang, Zhengcong Huang, Chenlin Lv, Shuxiu Xu, Zekai Zhuang, Anyan Yang, Jing Li, Kai Wu, Yumei He   +12 more
wiley   +1 more source

Review of the Recent Literature on the Mode of Delivery for Singleton Vertex Preterm Babies

Journal of Pregnancy, 2011
Choosing the safest method of delivery and preventing preterm labour are obstetric challenges in reducing the number of preterm births and improving outcomes for mother and baby.
Smriti Ray Chaudhuri Bhatta, Remon Keriakos   +1 more
doaj   +1 more source

The effects of childbirth on the pelvic-floor [PDF]

, 2000
Basically, vaginal delivery is associated with the risk of pelvic floor damage. The pelvic floor sequelae of childbirth includes anal incontinence, urinary incontinence and pelvic organ prolapse.
Allen RE, Anthony S, Frudinger A, Frudinger A, Gilpin S, Jackson S, Johanson RB, King JK, Labrecque M, Mac Arthur C, Mant J, Pigne A, Rasmussen KL, Rockner G, Sleep J, Smith AR, Snooks SJ, Sultan AH, Sultan AH, van Geelen J, Vessey MP, Viktrup L, Viktrup L, Wilson PD, Zetterstrom JP   +24 more
core   +1 more source

Connexin43 Deficiency Leads to Ventricular Arrhythmias by Reprogramming Proline Metabolism

Advanced Science, EarlyView.
The study demonstrated that connexin43 (Cx43) knockout caused arrhythmic phenotype and decreased proline content in vitro and in vivo. Mechanistically, Cx43 interacts with the amino acid transporter SNAT2 (sodium‐dependent neutral amino acid transporter), and its deficiency disrupts proline transport and metabolism.
Hangying Ying, Hangping Fan, Yunhe Wang, Ruhong Jiang, Dongsheng Cai, Hui Cheng, Hao Wang, Chenyang Jiang, Ping Liang   +8 more
wiley   +1 more source

Association between intravenous fluids during labor and primary postpartum hemorrhage: A retrospective cohort study

Acta Obstetricia et Gynecologica Scandinavica
Introduction There is a major research gap relating to the impact of intravenous (IV) fluids administration during labor on maternal and neonatal outcomes.
Belinda R. Bruce, Heather L. Shepherd, Saleem Ahmed Khan, Charlotte R. Haunton, Julie Leask, Bradley S. De Vries   +5 more
doaj   +1 more source

Reproductive outcomes following induced abortion : a national register-based cohort study in Scotland [PDF]

, 2012
PMID: 22869092 [PubMed] Free full textPeer ...
Bhattacharya, Siladitya, Bhattacharya, Sohinee, Lee, Amanda Jane, Lowit, Alison, Mahmood, Tahir, Raja, Edwin Amalraj, Templeton, Allan   +6 more
core   +2 more sources