Results 101 to 110 of about 1,852,348 (320)

GALNT10 Affects O‐Glycosylation of IGFBP7 to Promote Tumor Vascular Remodeling and Metastasis of Ovarian Cancer

Advanced Science, EarlyView.
The glycosyltransferase GALNT10 facilitates ovarian cancer metastasis through the induction of tumor cell EMT and tumor vascular dysfunction. GALNT10 enhanced the extracellular secretion of IGFBP7 through O‐GalNAc glycosylation modification at the T188 site, which subsequently interacts with CD93 on endothelial cells, leading to vascular remodeling ...
Yanan Zhang, Ayala Zuha, Zhangxin Wu, Aiping Luo, Bixia Jin, Qinkun Sun, Yuan Li, Qiyu Liu, Hongyan Guo, Chunliang Shang   +9 more
wiley   +1 more source

Severe acute maternal morbidity and associated deaths in conflict and post-conflict settings in Africa [PDF]

, 2012
SETTING:  Five hospitals in four conflict and post-conflict countries (Democratic Republic of Congo, Somaliland, Sierra Leone and Burundi). OBJECTIVES:  To report among hospital deliveries: 1) the proportion of severe acute maternal morbidity (SAMM), 2 ...
Hinderaker, S G, Manzi, M, Tamura, M, Van Den Bergh, R, Zachariah, R   +4 more
core   +2 more sources

TP53BP2 Promotes Placental Autophagy and Preeclampsia via G9a and DNMT1 Cooperatively Modulating E2F1

Advanced Science, EarlyView.
G9a, and DNA Methyltransferase1 (DNMT1) cooperatively modulates E2F1 on the promoter of tumor suppressor p53‐binding protein 2 (TP53BP2) increased autophagy in preeclampsia. TP53BP2 promotes autophagy in trophoblasts through DNA methylation and H3K9me2‐mediated transcriptional regulation.
Nan Jiang, Shaoju Jin, Shaoying Wen, Wen Zeng, Chen Wang, Jingyu Wang, Qingyun Song, Guizhong Li, Pengzhi Yin, Yuhui Liao, Yuee Chai, Huiping Zhang, Shengchao Ma   +12 more
wiley   +1 more source

Features of abdominal delivery in obstetric institutions of level III

Кубанский научный медицинский вестник, 2020
Aim. To evaluate and analyse features of abdominal delivery in maternal care institutions (level III) in Krasnodar Krai on the basis of M.S. Robson’ obstetric care criteria (2001) and indicators of cesarean section efficacy.Materials and methods.
M. V. Galustyan, I. I. Kutsenko, I. O. Borovikov   +2 more
doaj   +1 more source

Challenging the status quo: women's experiences of opting for a home birth in Andalucia, Spain [PDF]

, 2019
Objective To explore the perceptions, beliefs and attitudes of women who opted for a home birth in Andalusia (Spain). Background Home birth is currently an unusual choice among Spanish women.
Castro-Cardona, F., Escuriet, R., Leon-Larios, F., Nuno-Aguilar, C., Rocca-Ihenacho, L.   +4 more
core   +1 more source

Caspase‐3/GSDME‐Mediated Trophoblast Pyroptosis and Reciprocal Macrophage Polarization Contribute to Inflammation in Early‐Onset Preeclampsia

Advanced Science, EarlyView.
In trophoblast cells, T/S (TNFα + SM164) activated caspase‐3, which cleaved GSDME to switch apoptosis to pyroptosis, causing cell swelling, membrane rupture, and release of LDH, HMGB1, IL‐1β and IL‐18. These cytokines induced pro‐inflammatory macrophage polarization, which in turn reinforced pyroptotic signaling in trophoblasts, amplifying systemic ...
Baoying Huang, Weinan Deng, Shilei Bi, Yifan Wang, Zhaowei Tu, Lijun Huang, Lili Du, Lizi Zhang, Zhoushan Feng, Wei Sun, Tengfei Liu, Julia Kzhyshkowska, Haibin Wang, Jingsi Chen, Dunjin Chen, Shuang Zhang   +15 more
wiley   +1 more source

Mediolateral episiotomy and obstetric anal sphincter injuries in nullipara: a propensity score matching study

BMC Pregnancy and Childbirth
Background Obstetric anal sphincter injuries are a notable adverse outcome of vaginal deliveries, with incidence rates ranging from 0.25% to 6%. Key risk factors for these injuries include primiparity and operative vaginal deliveries.
Or Bercovich, Daniela Chen, Bar Narkis, Anat Pardo, Eran Hadar, Asnat Walfisch, Ohad Houri   +6 more
doaj   +1 more source

Obstetric Characteristics and Functional Outcomes in Women with Obstetric Anal Sphincter Injury

Journal of Nepal Health Research Council
Background: Obstetric anal sphincter injury is a complication of vaginal delivery, if left untreated, causes significant maternal morbidities; urinary problems and fecal/ flatus incontinence.
Shree Prasad Adhikari, Sandesh Poudel, Sapana Amatya Baidhya, Manisha Yadav   +3 more
doaj   +1 more source

Delivery as a traumatic event: prevalence, risk factors, screening & treatment [PDF]

, 2004
This review looks at the evidence for postnatal posttraumatic stress disorder (PTSD). Postnatal traumatic stress responses are divided into: appraisal of birth as traumatic, traumatic stress responses (severe symptoms of intrusions and avoidance that do
Ayers, S.
core  

Time-to-birth prediction models and the influence of expert opinions [PDF]

, 2019
Preterm birth is the leading cause of death among children under five years old. The pathophysiology and etiology of preterm labor are not yet fully understood.
A García-Blanco, BW Alleman, DA Silva De, E Celik, G Vandewiele, GJ Baaren Van, H Tan, H Watson, I Tekesin, J Beta, JM Schaaf, L Liu, LJ Meertens, M Allouche, M Mailath-Pokorny, M To, N Melamed, N Sananes, P Tsiartas, R Menon   +19 more
core   +1 more source