Results 131 to 140 of about 5,702,480 (359)

Albumin-binding dendritic siRNA improves delivery and efficacy to solid tumors in a melanoma model

Molecular Therapy: Nucleic Acids
Small interfering RNA (siRNA) therapeutics are a new class of drugs that is rapidly expanding to tackle various diseases. Extrahepatic delivery of siRNAs, especially to the parenchyma of solid tumors, is challenging with multiple strategies being ...
Hassan H. Fakih, Qi Tang, Ashley Summers, Katherine Y. Gross, Mohamad Omar Rachid, Ken Okamura, Nuria Martinez, Hanadi F. Sleiman, John E. Harris, Anastasia Khvorova   +9 more
doaj   +1 more source

Tumor microenvironment‐responsive delivery nanosystems reverse immunosuppression for enhanced CO gas/immunotherapy [PDF]

, 2023
Beibei Chen, Kangli Guo, Xiaoyi Zhao, Zhiwen Liu, Xu Chen, Nana Zhao, Fu‐Jian Xu   +6 more
openalex   +1 more source

ATG4B is required for mTORC1‐mediated anabolic activity and is associated with clinical outcomes in non‐small cell lung cancer

FEBS Open Bio, EarlyView.
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan, Bethany C. Guerra, Selina Uranga, Jessica M. Cardin, Steven E. Riechman, Mariana Janini Gomes, James D. Fluckey   +6 more
wiley   +1 more source

A Case Report of Successful Vaginal Delivery for Cauda Equina Syndrome Combined with Complex Regional Pain Syndrome

International Journal of Women's Health
Hwawon Lim,1 Yumi Shin,1 Hyunjo Kim,2 Bo Young Choi,1 Jee Yoon Park,1,3 Jae-Young Lim,2,4 Pyung-Bok Lee5 1Department of Obstetrics and Gynecology, Seoul National University Bundang Hospital, Seongnam, Republic of Korea; 2Department of Rehabilitation ...
Lim H, Shin Y, Kim H, Choi BY, Park JY, Lim JY, Lee PB   +6 more
doaj  

« Si on peut vous éviter une balafre […], vous accouchez comme une fleur ! » : réguler l’usage de la césarienne à l’hôpital public dans la France contemporaine

Anthropologie & Santé
The rate of Cesarean sections in France has remained stable over the last twenty years, after a continuous increase until the 1990s. Based on observations made in a public hospital and interviews with health professionals and patients who have given ...
Maëlys Bar
doaj   +1 more source

MOF-Based Polymeric Nanocomposite Films as Potential Materials for Drug Delivery Devices in Ocular Therapeutics [PDF]

, 2020
Jesús Gándara-Loe, Barbara Souza, Alexander Missyul, Geraldine Durango-Giraldo, Jin‐Chong Tan, Joaquín Silvestre‐Albero   +5 more
openalex   +1 more source

The association between SARS-CoV-2 infection and preterm delivery: a prospective study with a multivariable analysis [PDF]

, 2021
Óscar Martínez Pérez, Pilar Prats, Marta Muner Hernandez, María Begoña Encinas Pardilla, Noelia Pérez Pérez, Marı́a Rosa Hernández, Ana Villalba Yarza, Olga Nieto Velasco, Pablo Guillermo Del Barrio Fernandez, Laura Forcén Acebal, Carmen Lago, Alicia Martínez‐Varea, Begoña Muñoz Abellana, María Suárez Arana, Laura Fuentes Ricoy, Clara Martinez Diago, María Jesús Freire, Macarena Alférez Álvarez-Mallo, Cristina Casanova Pedraz, Onofre Alomar Mateu, Cristina Lesmes Heredia, Juan Carlos Wizner de Alva, Rut Bernardo Vega, Montserrat Macia Badia, Cristina Álvarez Colomo, Antonio Sánchez Muñoz, Laia Pratcorona, Rubén Alonso Saiz, M. López Rodríguez, Maria del Carmen Barbancho Lopez, Marta Ruth Meca Casbas, Óscar Vaquerizo Ruiz, Eva Morán Antolín, María José Núñez Valera, Camino Fernández, A. Tubau, Alejandra Maria Cano Garcia, Carmen Baena Luque, Susana Soldevilla Pérez, Irene Gastaca Abásolo, José Adanez García, María Teulón González, Alberto Puertas Prieto, Rosa Serna, María del Pilar Guadix Martín, Mónica Catalina Coello, Elena Perez, África Caño Aguilar, María Luisa de la Cruz, José Antonio Sainz‐Bueno   +49 more
openalex   +1 more source

Dietary nitrate and nitrite protect against doxorubicin‐induced cardiac fibrosis and oxidative protein damage in tumor‐bearing mice

FEBS Open Bio, EarlyView.
Chemotherapies such as doxorubicin can have toxic effects on healthy cardiovascular/heart tissue. Following up on a doxorubicin toxicity study in mice without tumors where nitrate water was cardioprotective (lessened toxicity), this study with tumor‐bearing mice undergoing doxorubicin treatment showed no negative effect of nitrate and nitrite on drug ...
Rama D. Yammani, Xiaofei Chen, Nildris Cruz‐Diaz, Xuewei Zhu, Swati Basu, Daniel B. Kim‐Shapiro, David R. Soto‐Pantoja, Leslie B. Poole   +7 more
wiley   +1 more source

« Après la césarienne, tu auras toujours des problèmes » : hiérarchisation des modèles de naissance en Inde du Nord

Anthropologie & Santé
Since the 2000s, Indian government programmes aimed at institutionalising childbirth have led to a medicalisation of childbirth. Among the various techniques, caesarean section is one of the most contested outcomes.
Lucia Gentile
doaj   +1 more source

From structural design to delivery: mRNA therapeutics for cancer immunotherapy [PDF]

, 2023
Feng Zhou, Lujia Huang, Shiqin Li, Wenfang Yang, Fangmin Chen, Zhixiong Cai, Xiaolong Liu, Wujun Xu, Vesa‐Pekka Lehto, Ulrich Lächelt, Rongqin Huang, Yang Shi, Twan Lammers, Wei Tao, Zhi Ping Xu, Ernst Wagner, Zhiai Xu, Haijun Yu   +17 more
openalex   +1 more source