Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Molecular Oncology, EarlyView.To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley +1 more source
Interplay between RNA‐protein interactions and RNA structures in gene regulation
FEBS Open Bio, EarlyView.Methodological advances in mapping transcriptome‐wide RNA‐protein interactions and RNA structures have started to uncover the potential of RNP conformations in gene regulation. Competing RNA–RNA, RNA‐protein and protein–protein interactions shape the compaction and function of RNPs throughout their lifetime and may provide novel therapeutic targets in ...
Jenni Rapakko +2 more
wiley +1 more source
Cysteine-activated hydrogen sulfide (H2S) delivery through caged carbonyl sulfide (COS) donor motifs
, 2018 Yu Zhao +2 more
openalex +2 more sources
Non-Viral Vector Mediated Gene Delivery: the Outsider to Watch Out For in Gene Therapy [PDF]
, 2019 Alengo Nyamay’Antu +3 more
openalex +1 more source
Unique risk factors for unplanned preterm delivery in the uterus transplant recipient [PDF]
, 2023 Liza Johannesson +3 more
openalex +1 more source
A general model for analysis of linear and hyperbolic enzyme inhibition mechanisms
FEBS Open Bio, EarlyView.We developed a general enzyme kinetic model that integrates these six basic inhibition mechanism onto a single one. From this model, we deduced a general enzyme kinetic equation that through modulation of simple parameters, γ (the relative inhibitor affinity for two binding sites) and β (the reactivity of the enzyme–substrate–inhibitor complex), is ...
Rafael S. Chagas, Sandro R. Marana
wiley +1 more source
Decentralized Caching and Coded Delivery with Distinct Cache Capacities
, 2017 Mohammad Mohammadi Amiri +2 more
openalex +2 more sources
Hypoxia-Responsive Mesoporous Nanoparticles for Doxorubicin Delivery [PDF]
, 2018 Shakera Khatoon +8 more
openalex +1 more source
Estimating blood loss during cesarean delivery: A comparison of methods
, 2022 Abdulrahim Gari +6 more
openalex +1 more source