Results 41 to 50 of about 342,375 (214)

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Association of birth by cesarean section with academic performance and intelligence in youth: A cohort study

Acta Obstetricia et Gynecologica Scandinavica, 2023
Introduction It is suggested that birth by elective cesarean section (CS) reduces the risk of birth‐related infant mortality and injury. Other studies suggest an increased risk of somatic immune‐related diseases among children born by CS such as asthma ...
Agnes K. Ladelund, Julie A. Slavensky, Frederik J. Bruun, Emilie Pi Fogtmann Sejer, Erik Lykke Mortensen, Steen Ladelund, Ulrik S. Kesmodel   +6 more
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Effect of trial of labor after previous cesarean delivery on maternal and neonatal outcomes：a meta⁃analysis

Huli yanjiu, 2019
ObjectiveTo systematically evaluate the effects of vaginal trial production after previous caesarean on maternal and neonatal outcomes.MethodsRelevant databases ,including of the CBM,CNKI,VIP,WanFang Data,PubMed,CENTRAL,Embase,Web of Science,CINAHL,were ...
ZHANG Qiushi, ZHU Tongmei
doaj  

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

GESTATIONAL SARS-COV-2 AND THE MODE OFDELIVERY: MINIREVIEW

Trakia Journal of Sciences
Purpose: The emergence of the SARS-CoV-2 coronavirus has posed untold challenges to medical systems, as pregnant women are more susceptible to its harmful effects.
R. S. Jasem Al-Dahwi, D. Kostadinova-Slavova, M. Angelova   +2 more
doaj   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Seeding and feeding: nutrition and birth-associated exposures shape gut microbiome assembly in breastfed infants

Gut Microbes
Gut microbiome establishment in early life is influenced by maternal, infant, and environmental factors, with disruptions linked to later disease risk. Although infant diet is a major determinant of microbial composition, longitudinal data in breastfed ...
Lisa F. Stinson, Isabella Norrish, Faith Mhembere, Ali Sadiq Cheema, Christopher A. Mullally, Matthew S. Payne, Donna T. Geddes   +6 more
doaj   +1 more source