Results 121 to 130 of about 659,509 (345)

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

The effect of digital adoption and service quality on business sustainability through strategic alliances at port terminals in Indonesia

Asian Journal of Shipping and Logistics
Effective port management is vital for a nation's economic growth. Amid global advancements, ports must ensure business sustainability across social, environmental, and economic domains due to regulations and market demands.
Dani Rusli Utama, Mohammad Hamsal, Rano Kartono Rahim, Asnan Furinto   +3 more
doaj   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

Provider Incentives and Delivery of Developmental Goods [PDF]

, 2010
We use a donor-provider-agent framework to study the delivery of developmental goods (i.e. aid, credit, technology transfer to poor). The need to provide incentives for the intermediate provider has been a key issue in the recent academic as well as non-academic discourses.
Mishra, Ajit, Sarangi, Sudipta
openaire  

Delivery of dangerous goods: Type III secretion in enteric pathogens

International Journal of Medical Microbiology, 2002
Type III secretion systems (TTSSs) of Gram-negative pathogens are molecular syringes that inject bacterial virulence factors directly into host cells. These virulence factors manipulate host cell pathways to aid bacterial survival within the host. Four important enteric pathogens use TTSSs to colonize and persist within the intestinal environment.
Michelle L, Zaharik, Samantha, Gruenheid, Andrew J, Perrin, B Brett, Finlay   +3 more
openaire   +2 more sources

New trends on urban goods movement: Modelling and simulation of e-commerce distribution [PDF]

In this paper, a modelling framework to complete the recent scientific works on urban goods modelling is proposed. More precisely, we introduce a substitution procedure that estimates the number of trips and the corresponding travelled distances for ...
Christian Ambrosini, Jean-Louis Routhier, Jesus Gonzalez-Feliu   +2 more
core  

VARIABLE ASSESSMENT OF THE TRANSPORT AND LOGISTICS SCHEME FOR THE DISTRIBUTION OF GOODS TO THE TRADE NETWORK

Municipal economy of cities
The distribution of goods to the trade network is a complex process that requires a careful approach to determining the hierarchical structure of the interaction of participants in the logistics chain and planning their activities.
V. Vdovychenko, A. Kuzmin, D. Zinoviev, O. Cherepakha, Yaroslav Vorontsov   +4 more
semanticscholar   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

The Relative Efficiency of Container Terminals in Small and Medium-Sized Ports in China

Asian Journal of Shipping and Logistics, 2015
The promotion of domestic consumption in China will gradually ramp up the small and medium-sized port container industry, and this will require greater port efficiency and an updated development strategy.
Zi-Yao Ding, Geon-Sik Jo, Ying Wang, Gi-Tae Yeo   +3 more
doaj   +1 more source

The delivery of goods as (modus acquirendi) of property [PDF]

Zbornik radova Pravnog fakulteta, Novi Sad, 2012
The delivery means the transfer of possession of property from one person, seller, to another, buyer. The seller delivers goods to buyer if he delivers them physically, if he makes symbolic delivery by delivering document of title to them (e.g. a bill of landing) or other means of control over them (e.g. the keys of warehouse in which they are stored),
openaire   +2 more sources