Results 61 to 70 of about 2,809,352 (301)

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source

Barriers to physical activity among pregnant women in China: a mixed methods study based on the COM-B model and the theoretical domains framework

BMC Public Health
Background Although physical activity has numerous benefits during pregnancy, most pregnant women remain physically inactive. This study aimed to explore barriers to physical activity among Chinese pregnant women through an integrated application of the ...
Linfei Ye, Fangfang Wang, Lin Li, Yuexia Liao, Xingchen Shang   +4 more
doaj   +1 more source

Clinical effect of moxibustion combined with acupoint application on early prevention of postpartum urinary retention in women with epidural analgesia and vaginal delivery

Pakistan Journal of Pharmaceutical Sciences
Background: Epidural analgesia increases postpartum urinary retention (PPUR) risk. This study assessed a combined acupuncture and acupoint application therapy for the prevention of PPUR.
Hong Wei, Jianhong Xue, Xiaying Zhang
doaj   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source

Current Experience with Obstetrical Events: Characteristics and the Effects of Nocturnal Periods

Clinical and Experimental Obstetrics & Gynecology
Background: The object is to analyze the influence of the nocturnal period and lunar phases on the frequency of obstetrical events in pregnant women. Methods: This was a retrospective, transversal observational study of 1409 births in a hospital from ...
Susana Blanco-López, Laura Peteiro-Mahía, Rocío Navas-Arrebola, Noelia López-Castiñeira, Sonia Pertega-Díaz, Teresa Seoane-Pillado   +5 more
doaj   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

FEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Anxiety in the Perinatal Period: Associated Factors

Clinical and Experimental Obstetrics & Gynecology
Background: Attention to mothers during pregnancy, childbirth, and postpartum has focused on the physical aspects, overlooking mental health, which is critical to maternal well-being and childbirth.
Rocío Navas-Arrebola, Susana Blanco-López, Laura Peteiro-Mahía, Noelia López-Castiñeira, Sonia Pertega-Díaz, Teresa Seoane-Pillado   +5 more
doaj   +1 more source

Simulation in Neonatal Resuscitation

Frontiers in Pediatrics, 2020
Approximately 1 in 10 newborns will require basic resuscitation interventions at birth. Some infants progress to require more advanced measures including the provision of positive pressure ventilation, chest compressions, intubation and administration of
Aisling A. Garvey, Aisling A. Garvey, Eugene M. Dempsey, Eugene M. Dempsey   +3 more
doaj   +1 more source

Delivery room management according to gestational age and existence of prenatal parental preferences for delivery room management.

, 2019
Delivery room management according to gestational age and existence of prenatal parental preferences for delivery room management.
Hélène Béhal (4318945), Laurence Foix L’Hélias (4281541), Elie Azria (104067), Caroline Diguisto (110792), Barthélémy Tosello (739604), Olivier Claris (333327), Monique Kaminski (323727), Cerise Levaillant (7325951), Laurence Caeymaex (192212), Pierre Bétrémieux (739606), Patrick Truffert (409488)   +10 more
core   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

FEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk, Gailing Ma, Robin Antrobus, Diego Manni, Marco Trevisan‐Herraz, Mustafa Khwaja, Max Brown, Gavin D. Richardson, Masaaki Komatsu, Daniel Erskine, Viktor I. Korolchuk, Tetsushi Kataura   +11 more
wiley   +1 more source