Results 61 to 70 of about 58,501 (253)

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

Relationship of Hospital Architecture to Nursing Staff Caring for Self, Caring for Patients, and Job Satisfaction

open access: yesInterdisciplinary Journal of Partnership Studies, 2016
Historically, the fields of architecture (design) and nursing (health) have been separate disciplines without much intersection. In recent years, the healthcare building boom has created a specialty practice for architects, focusing on healthcare design.
Mary Ann Hozak   +2 more
doaj   +1 more source

Process Evaluation of Facility Delivery Services in Northwest Ethiopia: In the Case of Public Health Centers

open access: yesInternational Journal of Women's Health, 2023
Tesfahun Zemene Tafere, Andualem Yalew Aschalew, Chalie Tadie Tsehay, Tsegaye Gebremedhin Department of Health Systems and Policy, Institute of Public Health, College of Medicine and Health Sciences, University of Gondar, Gondar, EthiopiaCorrespondence ...
Tafere TZ   +3 more
doaj  

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Robotic Applications for Safe Operations in Hospital Isolation Rooms

open access: yes
Hospital isolation rooms expose healthcare workers to infection risks during routine tasks like IV bag replacement and material delivery. This paper presents a teleoperated TIAGo robot system controlled via Bluetooth joystick through a modular ROS 2 ...
Antonio Bottalico   +2 more
core   +1 more source

Re-Imagining Labor and Delivery Facilities in Hospitals

open access: yes, 2023
This labor and delivery hospital wing has been redesigned with the woman’s needs in mind. Modern mothers want more natural birth experiences. There is many popular fads going around where women are having at home and underwater births.
Roberts, Kenley
core  

Parent psychological wellbeing in a single-family room versus an open bay neonatal intensive care unit.

open access: yesPLoS ONE, 2019
BACKGROUND:Studies of parents' psychological well-being in single-family rooms in neonatal intensive care units have shown conflicting results. AIMS:To compare emotional distress in the form of depression, anxiety, stress and attachment scores among ...
Bente Silnes Tandberg   +4 more
doaj   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

Developing family rooms in mental health inpatient units: an exploratory descriptive study [PDF]

open access: yes, 2015
Background: Family-friendly spaces for children and families to visit inpatient mental health units are recommended in international mental health guidelines as one way to provide service delivery that is responsive to the needs of parent-consumers and ...
Clair Edwards   +5 more
core   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

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