Results 191 to 200 of about 7,677,076 (348)

Multidrug delivery system based on polysaccharide nanocomplexes for controlled delivery of a combination of chemotherapeutics

open access: yes, 2019
Development of delivery systems able to hold and release a combination of bioactive compounds at the target site represents a strategy for improving the therapeutic outcomes and overcome the central issues in the multitherapeutic approach.
Özaltin, Kadir   +4 more
core  

The Tale of the Residual Tail: Insights From Continuous Intracranial Monitoring From Post‐Hippocampectomy Dynamics

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Subtotal hippocampal resection can leave residual hippocampal tissue, yet the immediate postoperative electrophysiologic evolution of such remnants is unknown. We describe a patient with drug‐resistant temporal lobe epilepsy in whom a hippocampal remnant was continuously monitored using a responsive neurostimulator (RNS) following subtotal ...
Patrick Hartnett   +5 more
wiley   +1 more source

Focus on Barangay Economic Development [PDF]

open access: yes
Because the barangay is considered to be the local government unit closest to the people in terms of access and proximity, its role in local service delivery cannot be undermined. Hence, it is important for a barangay to learn how to maximize and use its
Lavado, Rouselle F.   +2 more
core  

CAR T‐Cell Therapy in Neurology: A Scoping Review of Neuro‐Oncology, Autoimmune Diseases & Neurotoxicity

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Chimeric antigen receptor (CAR) T‐cell therapy has been investigated in neurological diseases, encompassing both central nervous system malignancies and autoimmune disorders, thereby extending its application beyond hematological cancers.
Omar Alqaisi   +5 more
wiley   +1 more source

Evaluation of Digital Technologies for Home‐Based Assessment in People With Amyotrophic Lateral Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Digital technologies hold promise for transforming healthcare by enhancing personalized treatments and offer valuable opportunities to improve patient care. Here, we evaluated several novel, self‐administered, home‐based, digital endpoints for their association with corresponding conventional standard clinical measures (primary) in ...
Arne Mueller   +14 more
wiley   +1 more source

Swellable/Erodible Delivery Systems for Time-Controlled Release of Drugs into the Gastrointestinal Tract

open access: yes, 2016
In oral delivery, it is often advantageous to have the onset of drug release delayed for a programmable period of time following administration. This would indeed allow the chronotherapeutic needs of several pathologies with night or early morning ...
A. Maroni
core  

Onasemnogene Abeparvovec in Patients With SMA: Interim Results of the RESTORE Registry in Japan

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective There are limited real‐world data regarding the safety and effectiveness of onasemnogene abeparvovec (OA; Zolgensma) infusion, a one‐time gene replacement therapy, for Japanese patients with spinal muscular atrophy (SMA). We aimed to improve understanding of the real‐world outcomes for OA in Japan.
Kayoko Saito   +8 more
wiley   +1 more source

Scoping review of e-cigarette use in the perioperative setting: a protocol. [PDF]

open access: yesBMJ Open
Harrogate SR   +4 more
europepmc   +1 more source

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