Molecular Oncology, EarlyView.This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi +6 more
wiley +1 more source
Optimal delivery time for patients with diet-controlled gestational diabetes mellitus: a single-center real-world study. [PDF]
BMC Pregnancy Childbirth, 2022 Yin Z, Li T, Zhou L, Fei J, Su J, Li D.
europepmc +1 more source
Time and place of delivery in civil proceedings
Zbornik Radova Pravnog Fakulteta u Splitu, 2010 The most important principle of civil procedure is the right to be heard before a court which is with good reason being viewed as an essential part of any proceeding in accordance with the rule of law.
Dinka Šago
doaj
Molecular Oncology, EarlyView.We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee +3 more
wiley +1 more source
A neural network-based model for estimating the delivery time of oxygen gas cylinders during COVID-19 pandemic. [PDF]
Neural Comput Appl, 2022 Ghaithan AM +3 more
europepmc +1 more source
Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer
Molecular Oncology, EarlyView.Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim +7 more
wiley +1 more source
Time-controlled oral delivery systems for colon targeting
, 2006 A review. In recent years, many research efforts have been spent in the achievement of selective delivery of drugs into the colon following oral administration. Indeed, colonic release is regarded as a beneficial approach to the pharmacol. treatment or
A. Maroni +3 more
core +1 more source
Developing an accurate model of spot-scanning treatment delivery time and sequence for a compact superconducting synchrocyclotron proton therapy system. [PDF]
Radiat Oncol, 2022 Zhao L +8 more
europepmc +1 more source
Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy
Molecular Oncology, EarlyView.We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen +19 more
wiley +1 more source
Machine Learning for Investigation on Endocrine-Disrupting Chemicals with Gestational Age and Delivery Time in a Longitudinal Cohort. [PDF]
Research (Wash D C), 2021 Luan H +9 more
europepmc +1 more source