Results 31 to 40 of about 114,643 (158)

Credibility and expectancy associated with ultra‐brief and standard‐length digital treatments: A preliminary examination of impact on treatment outcome

British Journal of Clinical Psychology, EarlyView.
Abstract Objective Ultra‐brief treatments (i.e., three or fewer sessions/modules) are associated with reductions in depression and anxiety symptoms, though the mechanisms underlying their effects are unclear. Research has yet to compare how perceptions of treatment credibility and outcome expectancy (i.e., how suitable and effective the treatment will ...
Melanie Seshadri, Blake F. Dear, Madelyne A. Bisby   +2 more
wiley   +1 more source

Covalent drug discovery: Progress against key targets, emerging strategies and lessons learnt

British Journal of Pharmacology, EarlyView.
Abstract Covalent drug discovery is currently experiencing a boom in industrial and academic interest. To date, at least 75 covalent drugs have received regulatory approval, targeting both traditional target classes and more challenging proteins for which other approaches failed. In many cases, unique aspects of covalent targeting are essential for the
Charles P. Brown, Alan Armstrong, David J. Mann   +2 more
wiley   +1 more source

Advancing conservation breeding programs for marine invertebrates

Conservation Biology, EarlyView.
Abstract In the face of ecosystem change and biodiversity loss caused by climate change and other stressors, conservation breeding, or captive breeding, with the aim of reintroduction for wild population recovery, is an emerging tool for preventing species’ extinction and rehabilitating ecosystems.
Elora H. López‐Nandam, Bart Shepherd, Kylie Lev, Rebecca Albright   +3 more
wiley   +1 more source

Structural insights into xyloglucan recognition by an ABC transporter from a Gram‐positive, thermophilic bacterium

The FEBS Journal, EarlyView.
Athe_2052 is an ABC transporter substrate‐binding protein that recognizes xyloglucan heptasaccharide (XXXG), a soluble breakdown product of plant xyloglucan. The crystal structure of Athe_2052, together with binding assays and computational modeling, shows how XXXG is recognized by this sugar transporter.
Hansen Tjo, Virginia Jiang, Philip D. Jeffrey, Angela Zhu, A. James Link, Jerelle A. Joseph, Jonathan M. Conway   +6 more
wiley   +1 more source

Economic policy uncertainty and international corporate leasing

Journal of Financial Research, EarlyView.
Abstract We examine the effect of economic policy uncertainty (EPU) on the corporate lease decision using an international sample of 19 countries. The use of operating leases increases when EPU is heightened. The documented leasing increase is more pronounced for financially constrained firms, firms facing greater operating volatility, or those that ...
Goutham Abotula, Douglas (DJ) Fairhurst, Yoonsoo Nam   +2 more
wiley   +1 more source

Autoregressive Hypergraph

Journal of Time Series Analysis, EarlyView.
ABSTRACT Traditional graph representations are insufficient for modelling real‐world phenomena involving multi‐entity interactions, such as collaborative projects or protein complexes, necessitating the use of hypergraphs. While hypergraphs preserve the intrinsic nature of such complex relationships, existing models often overlook temporal evolution in
Xianghe Zhu, Qiwei Yao
wiley   +1 more source

Do deepfakes, digital replicas and human digital twins justify personality rights?

The Journal of World Intellectual Property, EarlyView.
Abstract Unauthorised deepfakes are deeply problematic, from the spreading of misinformation to non‐consensual pornographic content. This paper asks whether deepfakes, digital replicas and human digital twins justify personality rights. To address this question, it examines the harms that deepfakes can cause through disinformation, demeaning content ...
Hayleigh Bosher
wiley   +1 more source

Integrative revision of the Australian carrion‐breeding Calliphorinae (Diptera: Calliphoridae): Revision of the Calliphora stygia‐ and ochracea‐groups

Medical and Veterinary Entomology, EarlyView.
The Australian carrion‐breeding Calliphorinae are revised using an integrative approach combining morphology and mitogenomics. A new taxonomic key, morphological images and verified mitogenomic data, including COX1 barcodes, are provided to support the identification of species.
Liam B. D. C. Foley, James F. Wallman, Krzysztof Szpila, Kelly A. Meiklejohn, Nikolas P. Johnston   +4 more
wiley   +1 more source

Exploring the Prevalence and Clinical Relevance of Health Literacy in Severe Obesity: A Scoping Review

Obesity Reviews, EarlyView.
ABSTRACT Recent studies suggest that health literacy (HL) may play an important role in management of individuals living with severe obesity (BMI ≥ 40 kg/m2), but to date, there has been no attempt to synthesize characteristics and outcomes of these studies.
Andrea Xia, Supreet Saluja, Danielle M. Muscat, Philayrath Phongsavan, Kate McBride, Kathryn Williams   +5 more
wiley   +1 more source

Time‐series multi‐omics analysis of micronutrient stress in Sorghum bicolor reveals iron and zinc crosstalk and regulatory network conservation

Plant Biology, EarlyView.
Overlap between Fe and Zn responsive gene regulatory networks (GRNs) were found, indicative of micronutrient crosstalk, and conservation of root and leaf GRNs and genes suggests strong constraint on homeostasis networks in plants. Abstract Micronutrient stress impacts growth, biomass production, and grain yield in crops.
A. Mishra, A. Bhat, S. Kumari, R. Sharma, J. Braynen, D. Tadesse, S. El Alaoui, S. Seaver, N. Grosjean, D. Ware, M. Xie, T. Paape   +11 more
wiley   +1 more source