Results 191 to 200 of about 98,752 (276)

Circadian and Sleep-Wake Modulation of Functional Connectivity Across Brain Oscillations and States Linked to Cognition in Humans

Lazar AS, Lazar ZI, Santhi N, Lo JC, Groeger JA, Dijk D.   +5 more
europepmc   +1 more source

Tonic-clonic seizures induce hypersomnia and suppress rapid eye movement sleep in mouse models of epilepsy. [PDF]

Sleep Adv
Wang R, Teng S, Turanchik M, Zhen F, Peng Y.   +4 more
europepmc   +1 more source

Human Brain Vasculature‐on‐a‐Chip Model Constructed With Microvessels Isolated From Cryopreserved Postmortem Human Brain Tissue

Advanced Healthcare Materials, EarlyView.
This manuscript describes the cultivation of viable microvessels from cryopreserved human brain tissue. When embedded in hydrogels and cultured in microfluidic devices, these microvessels exhibit complex architectures reminiscent of arterioles and capillaries, can be perfused, and display intact barrier function. Collectively, these results demonstrate
Brian J. O'Grady, A. Scott McCall, Samuel Cullison, Daniel Chavarria, Matthew S. Schrag, Ethan S. Lippmann   +5 more
wiley   +1 more source

Suk-SaiYasna Remedy, a Traditional Thai Medicine, Mitigates Stress-Induced Cognitive Impairment via Keap1-Nrf2 Pathway. [PDF]

Int J Mol Sci
Masraksa W, Daodee S, Monthakantirat O, Boonyarat C, Khamphukdee C, Kwankhao P, Mading A, Muenhong P, Maneenet J, Awale S, Matsumoto K, Chulikhit Y.   +11 more
europepmc   +1 more source

Dual‐Functional Polyphosphoesters for Gene Delivery: Synergistic Effects of Guanidinium and Hydrophobic Side Chains in Degradable Polymers

Advanced Healthcare Materials, EarlyView.
This study presents guanidinium‐ and indole‐functionalized polyphosphoesters as degradable, non‐viral gene delivery vectors. Through precise tuning of charge density and hydrophobicity, these polymers form stable polyplexes with low toxicity. Remarkably, minor structural changes yield up to 200‐fold differences in transfection efficiency, highlighting ...
Markus Kötzsche, Andreas Dzierza, Jan Egger, Timo Rheinberger, Christin Weilandt, Frederik R. Wurm, Ivo Nischang, Dagmar Fischer, Kalina Peneva   +8 more
wiley   +1 more source

Effect of chronic benzodiazepine and benzodiazepine receptor agonist use on sleep architecture and brain oscillations in older adults with chronic insomnia. [PDF]

Sleep
Barbaux L, Perrault AA, Cross NE, Weiner OM, Es-Sounni M, Pomares FB, Tarelli L, McCarthy M, Maltezos A, Smith D, Gong K, O'Byrne J, Yue V, Desrosiers C, Clerc D, Andriamampionona F, Lussier D, Gilbert S, Tannenbaum C, Gouin JP, Dang-Vu TT.   +20 more
europepmc   +1 more source

A Versatile Engineering Platform for the Fabrication of Prosthetic Venous Valves Using Electrospinning

Advanced Healthcare Materials, EarlyView.
Percutaneous prosthetic venous valves are fabricated by embedding stents in an electrospun matrix that extends luminally to form leaflets. The design shields leaflets from hyperplastic cells, isolates struts from blood contact, and avoids discrete anchoring points.
Dario Arcuti, Salma Mansi, Dominic Biebl, Malin Reuter, Maximilian Grab, José Carlos Rodríguez‐Cabello, Petra Mela   +6 more
wiley   +1 more source

The Role of Insular Cortex and Prefrontal Cortex in the Pathogenesis of Fibromyalgia: Biochemical and Electrophysiological Rodent Study. [PDF]

Neurochem Res
Abouelnaga AF, Hussein AM, Abass M, Shafiek MZ, Zaki HF, Mohamed AF, Ibrahim WW.   +6 more
europepmc   +1 more source

Tunable Bioresorbable Scaffolds With Marine Sulfated Polysaccharides for Small‐Caliber Vascular Grafts: A Multi‐Layered Strategy Combining Electrospinning and 4‐Axis Printing

Advanced Healthcare Materials, EarlyView.
A multilayered small‐caliber vascular scaffold combining electrospinning and 4‐axis printing is developed and biofunctionalized with marine sulfated polysaccharides from Holothuria tubulosa. The resulting construct exhibits enhanced hemocompatibility, tunable mechanical properties, and supports endothelial and smooth muscle cell adhesion and ...
Gabriele Obino, Alberto Sensini, Tim ten Brink, Gabriele Nieddu, Tristan Bodet, Giovanni Andrea Deiana, Martijn van Griensven, Marilena Formato, Antonio J. Lepedda, Lorenzo Moroni   +9 more
wiley   +1 more source

Protective effects of jujube seed extract against oxidative stress in HT22 cells and its sleep-promoting action through GABAergic receptors. [PDF]

J Food Drug Anal
Chung SH, Kim H, Kim S, Jeong PY, Lee H.
europepmc   +1 more source