Results 91 to 100 of about 20,633 (240)

Structural and Biological Insights Into Copper(I) Phosphane Complexes With Boron‐Phenylated Poly(3‐(CF3)Pyrazolyl)‐ and Poly(6‐(CF3)‐2‐pyridyl)‐Borates

Chemistry – A European Journal, EarlyView.
This study reports six new copper(I) complexes with unusual coordination and strong anticancer activity against a panel of human cancer cell lines derived from different solid tumors. The most active compounds outperform cisplatin, even in resistant cells, by inhibiting protein disulfide isomerase and inducing redox stress that triggers non‐apoptotic ...
Vo Quang Huy Phan, Jo’ Del Gobbo, Mukundam Vanga, Deepika V. Karade, Cristina Marzano, Valentina Gandin, Laura Rigon, Carlo Santini, Maura Pellei, H. V. Rasika Dias   +9 more
wiley   +1 more source

Profiling endogenous airway proteases and antiproteases and modeling proteolytic activation of Influenza HA using in vitro and ex vivo human airway surface liquid samples.

PLoS ONE
Imbalance of airway proteases and antiproteases has been implicated in diseases such as COPD and environmental exposures including cigarette smoke and ozone.
Stephanie A Brocke, Boris Reidel, Camille Ehre, Meghan E Rebuli, Carole Robinette, Kevin D Schichlein, Christian A Brooks, Ilona Jaspers   +7 more
doaj   +1 more source

Interfacial adsorption characteristics of surfactant‐modified nanoparticles: Equilibrium and dynamic effects of salinity at the oil–water interface

The Canadian Journal of Chemical Engineering, EarlyView.
Surfactant‐modified nanoparticles adsorb at the oil–water interface, enabling interfacial stabilization and microemulsion formation. Abstract This study systematically investigated the interfacial behaviour of silicon dioxide (SiO2) and aluminium oxide (Al2O3) nanoparticles (NPs) functionalized with cationic (CTAB), anionic (SDS), and nonionic (Triton ...
Behrooz Ahmadi, Eghbal Sahraei, Amir H. Mohammadi   +2 more
wiley   +1 more source

PEK14: A Kinesin‐4 Necessary for Male‐Derived Fertility in Arabidopsis thaliana

Cytoskeleton, EarlyView.
ABSTRACT Of the 61 kinesins annotated in Arabidopsis thaliana, many are still without assigned function. Here, we have screened an insertional mutant library of Arabidopsis pollen‐expressed kinesins for fertility defects. Insertional mutants for three kinesins showed a significant reduction in seed set.
Isabella N. Mendes, Norman R. Groves, Jessica Z. Li, Lily N. Thompson, Brian J. Smith, Aman Y. Husbands, Iris Meier   +6 more
wiley   +1 more source

Detection of a Distinct Erythropoietin (EPO) Profile After Isoelectric Focusing in Patients With Familial Erythrocytosis

Drug Testing and Analysis, EarlyView.
A basic EPO IEF profile was identified in patients with familial erythropoiesis linked to mutations in noncoding parts of EPO gene. Comparison of blood and urine EPO profiles from these patients differed from adult wild‐type EPO (WT) and from Eprex‐administered patients. Patients' EPO do not differ from WT EPO after analysis using SDS‐PAGE/SAR‐PAGE. It
Laurent Martin, Salam Idriss, Nada Maaziz, Soizic Huerre, Lamine Redouane Mekacher, Kahina Lahmek, François Girodon, Betty Gardie, Magnus Ericsson, Alexandre Marchand   +9 more
wiley   +1 more source

Biophysical processes of morphogenesis in lizard lungs

Developmental Dynamics, EarlyView.
Abstract Background The lungs of squamate reptiles (lizards and snakes) are highly diverse, exhibiting single chambers, multiple chambers, transitional forms with two to three chambers, along with a suite of other anatomical features, including finger‐like epithelial projections into the body cavity known as diverticulae.
Kaleb Hill, Aaron H. Griffing, Michael A. Palmer, Bezia Lemma, Aria S. Lupo, Tony Gamble, Natalia A. Shylo, Andrej Košmrlj, Paul A. Trainor, Celeste M. Nelson   +9 more
wiley   +1 more source

Out-of-equilibrium charge redistribution in a copper-oxide based superconductor by time-resolved X-ray photoelectron spectroscopy

Scientific Reports
Charge-transfer excitations are of paramount importance for understanding the electronic structure of copper-oxide based high-temperature superconductors. In this study, we investigate the response of a Bi $$_2$$ 2 Sr $$_2$$ 2 CaCu $$_2$$ 2 O $$_{\textrm{
Denny Puntel, Dmytro Kutnyakhov, Lukas Wenthaus, Markus Scholz, Nils O. Wind, Michael Heber, Günter Brenner, Genda Gu, Robert J. Cava, Wibke Bronsch, Federico Cilento, Fulvio Parmigiani, Federico Pressacco   +12 more
doaj   +1 more source

Loss of Twist1 leads to disruption of ciliary length, endocytic vesicle dynamics, and cell–cell junctions during neural tube formation

Developmental Dynamics, EarlyView.
Abstract Background Endocytosis constitutes a fundamental cellular process governing development through coordinated regulation of plasma membrane remodeling and ciliogenesis, processes essential for cell shape changes and tissue development. Although Twist1 null embryos display complete cranial neural tube (NT) closure defects and conditional knockout
Derrick Thomas, Brittany M. Hufft‐Martinez, Zarna Lalwani, Vi Pham, Mary Elmeniawi, An J. Tran, Jianming Xu, Irfan Saadi, Walid D. Fakhouri   +8 more
wiley   +1 more source

Design of HAWT Rotor for Non‐Uniform Inflow Conditions: A Theoretical and Experimental Approach for Shear Flow

Energy Science &Engineering, EarlyView.
This paper aims to provide a robust design approach for HAWTs operating in shear flow. This study fills a critical research gap by integrating BEM and vortex theories for blade design in non‐homogeneous inflow conditions. The authors of the paper made an effort to develop and test an experimentally unsophisticated model of a turbine working in shear ...
Agnieszka Dorota Woźniak, Piotr Strzelczyk, Taeseong Kim   +2 more
wiley   +1 more source

Fabrication of electrospun PVDF nanofibrous membrane for filtration of coconut inflorescence sap

Food Biomacromolecules, EarlyView.
Electrospinning conditions for polyvinylidene difluoride (PVDF) nanofibrous membrane were optimized. The polymer solution's properties were analyzed. The developed membranes' average pore size was 478–543 nm. A fabricated membrane was used for the filtration of coconut inflorescence sap.
Sarangapany Ashwin Kumar, Paramasivam Santhoshkumar, Jeyan Arthur Moses   +2 more
wiley   +1 more source