Results 221 to 230 of about 54,944 (282)

Towards Mechanism‐Informed Treatments for Mental Health

Journal of Neurochemistry, Volume 170, Issue 5, May 2026.
Neuropsychiatric disorders impose a major global health burden, and current treatments, which historically mostly targeted dopamine and serotonin dysfunctions, often provide only partial, symptomatic relief. This review highlights emerging evidence that additional neuromodulator systems, including acetylcholine, norepinephrine, and endocannabinoids ...
Iker Bengoetxea de Tena, Farhanah Nabilah Sallie, Arvie Rodriguez Abiero, Beatrice Rizzi, Leandro Gabriel Champarini, Elisa Corti, Gianluca Masella, Ariel L. Dunn, Luisa Bandeira Binder, Tyler J. Wenzel, Agustin I. Robles, Roberta G. Anversa, Cécilia Tremblay, Aliance Romain Fokoua, Randriely Merscher Sobreira de Lima, Mateus D'Ávila, Trang T. T. Truong, Jessica C. Pierce, Rui S. Rodrigues, Luis Dinamarca‐Villarroel, Felipe Borges Almeida, Aino‐Kaisa Piironen, Andrey F. L. Aguiar, Andrés M. Jaramillo, Lucas Santos, Anja de Lange, David J. Nutt, Andrew J. Lawrence   +27 more
wiley   +1 more source

Key Insights From the International ICU Diary Conference 2025

Nursing in Critical Care, Volume 31, Issue 3, May 2026.
ABSTRACT We report on the 2025 International ICU Diary Conference that provided a comprehensive update on current knowledge, innovations and global practices related to ICU diaries. Held in a 6‐week online format, the event featured 23 speakers and was attended by mean 69.7 (SD 20.5) participants per session. Topics included development of ICU diaries,
Peter Nydahl, Bev Ewens, Anne‐Sophie Debue, Xavier Fiorilla, Kristin Gabriel, Alessandro Galazzi, Louise Gallie, Nikolas Groth, Carly Hickey, Mark Hudson, Fiona Lynch, Nicola Maxwell, Margo van Mol, Caroline Renner, Louise Rose, Kate Tantam, Lioudmila Karnatovskaia, Christina Jones   +17 more
wiley   +1 more source

Early Sedation Intensity and Psychological Outcomes in Critically Ill Adults

Nursing in Critical Care, Volume 31, Issue 3, May 2026.
ABSTRACT Background Long‐term psychological impairment is a major concern for intensive care unit (ICU) survivors. Early deep sedation during mechanical ventilation has been associated with poor short‐term outcomes and mortality after ICU discharge; however, its relationship with psychological outcomes remains unclear.
Mikiko Iwatani, Michiko Morimoto
wiley   +1 more source

The development of positron emission tomography (PET) tracer for glutamate AMPA receptors and its application to human biology and clinics

Psychiatry and Clinical Neurosciences, Volume 80, Issue 5, Page 367-373, May 2026.
Psychiatric and neurological disorders severely compromised patients' quality of life. Despite their urgent needs, the development of diagnostics and therapeutics based on the biological basis has made only little progress. This is due to limited evidence on the biological basis of these disorders in humans. Synapses are fundamental structural units of
Mai Hatano, Hiroki Abe, Takuya Takahashi
wiley   +1 more source

Challenges in the End‐of‐Life Care for Patients With Severe Persistent Mental Illness: A Case Series

Psychogeriatrics, Volume 26, Issue 3, May 2026.
ABSTRACT Introduction Despite reduced life expectancy and high rates of comorbidity, individuals with severe persistent mental illness (SPMI) face significant disparities in healthcare access and quality, which extends to palliative and end‐of‐life (EOL) care.
Kaushadh Jayakody, Isha Bajaj, Doug Blomeley   +2 more
wiley   +1 more source