Results 1 to 10 of about 32,830 (201)

Clinical, Neuropsychological, and Neuroimaging Features of Peruvian Patients with Primary Progressive Aphasia [PDF]

Alzheimers Dement
Abstract Background Primary progressive aphasias (PPA) are a group of neurodegenerative syndromes primarily characterized by the progressive loss of language. Despite established diagnostic criteria, identification can be challenging, especially in regions with limited resources and few studies, such as Latin America.
Bustamante‐Paytan D, Huilca J, Brown G, Albujar‐Pereira M, Aguero K, Verastegui G, Yauri Z, Bartolo P, Bendezu D, Lipa‐Pari K, Montesinos R, Custodio N.   +11 more
europepmc   +2 more sources

Assessing the Overlap in Diagnostic Criteria for Primary Progressive Aphasia in a Latin American Population [PDF]

Alzheimers Dement
Abstract Background Primary progressive aphasias (PPA) are characterized by a progressive deterioration of language. Despite the establishment of international criteria in 2011 defining three variants (semantic, nonfluent, and logopenic), these variants can present overlapping symptoms, making their identification and differentiation challenging.
Bustamante‐Paytan D, Huilca J, Brown G, Albujar‐Pereira M, Aguero K, Verastegui G, Yauri Z, Bartolo P, Bendezu D, Lipa‐Pari K, Montesinos R, Custodio N.   +11 more
europepmc   +2 more sources

Prevenção da demência com abordagens multimodais [PDF]

Alzheimers Dement
Abstract Background Dementia, including Alzheimer's Disease (AD), is a growing public health challenge with significant impacts on individuals and healthcare systems (CRIVELI, 2023). Prevention through multimodal strategies is essential to mitigate this epidemic (ROSENBER, 2020). The complexity of dementia requires approaches that simultaneously target
de Oliveira Alves J.
europepmc   +2 more sources

Implementing a Training Program for Cognitive and Neuropsychological Assessments in a Latin America country [PDF]

Alzheimers Dement
Abstract In the coming decades, the number of dementia cases is projected to increase worldwide. This public health issue will significantly impact low‐ and middle‐income countries, such as those in Latin America, due to their aging populations.
Verastegui G, Bustamante‐Paytan D, Montesinos R, Custodio N, Tosto G.   +4 more
europepmc   +2 more sources

Clinical characterization of probable Dementia with Lewy Bodies based on the initial clinical presentation in a Latin American Low‐ and Middle‐ Income Country [PDF]

Alzheimers Dement
Abstract Background Dementia with Lewy Bodies (DLB) is a specific type of dementia associated with the accumulation of alpha‐synuclein protein in the brain. The disease often presents heterogeneously in its early stages, and little is known about how this variability affects its progression.
Custodio N, Malaga M, Bustamante‐Paytan D, Huilca J, Aguero K, Verastegui G, Bartolo P, Bendezu D, Yauri Z, Montesinos R.   +9 more
europepmc   +2 more sources

Clinical Validation and Standardization of the Brain Health Assessment in the Tablet‐Based Cognitive Assessment Tool (BHA‐TabCAT) in Peruvian Older Adults [PDF]

Alzheimers Dement
Abstract Background Detecting cognitive decline presents a significant challenge for researchers and clinicians, particularly in older adults with low educational levels or different sociocultural characteristics. Additionally, traditional normative data may under‐ or overestimate preliminary diagnoses in these populations, due its non‐use of measures ...
Muñoz‐Najar A, Montemurro M, del Carmen Tejada M, Rivera‐Fernandez C, Sanchez‐Fernandez M, Custodio N, Lanata S, Soto‐Añari M.   +7 more
europepmc   +2 more sources

Relationship between genetic risk and p‐tau concentration on cognitive performance in a multiethnic population from Peru [PDF]

Alzheimers Dement
Abstract Background The presence of APOE 4 is considered the main genetic risk factor for the development of dementia. Additionally, plasma p‐tau has been shown to be an important biomarker associated with Alzheimer's disease. However, these factors have been understudied in Latin American ethnic minorities, such as the Quechuas and Aymaras.
Rivera‐Fernandez C, Custodio N, Montesinos R, Muñoz‐Najar A, Reyes‐Dumeyer D, Tosto G, Soto‐Añari M.   +6 more
europepmc   +2 more sources

Cognitive and Neuropsychiatric features of a Frontotemporal Dementia Cohort in Peruvian Population [PDF]

Alzheimers Dement
Abstract Background The prevalence of frontotemporal dementia (FTD) is 1.9% over 65 years. There is a considerable delay in the diagnosis of FTD and a high rate of misdiagnosis in Latin America. We describe cognitive and neuropsychiatric features in a Peruvian cohort.
Castro‐Suarez S, Zegarra‐Valdivia J, Guevara‐Silva E, Caparo‐Zamalloa C, Palomino‐Lescano H, Cuenca J, Alvarez‐Toledo K, Illanes‐Manrique M, Custodio N, Lanata S, Meza‐Vega M, Cornejo‐Olivas M.   +11 more
europepmc   +2 more sources

A machine learning approach for a multidimensional analysis of functional phenotype allows for a better measurement of dementia and its severity [PDF]

Alzheimers Dement
Abstract Background Functional impairment (FI) is a key component in diagnosing and monitoring the severity of neurodegenerative dementia (ND). It manifests in several dimensions, such as everyday cognition, mobility, social functioning, and activities of daily living (ADLs).
Muñoz C, Custodio N, Montesinos R, Custodio B, Bustamante‐Paytan D, Dominguez C, Gallardo Á, Campo C, Lillo P, Farías G, Cerda M, Slachevsky A.   +11 more
europepmc   +2 more sources

Tratamento da demência: recomendações do Departamento Científico de Neurologia Cognitiva e do Envelhecimento da Academia Brasileira de Neurologia

Dementia & Neuropsychologia, 2022
RESUMO Atualmente não há tratamento curativo para as demências neurodegenerativas ou para a demência vascular, mas algumas intervenções farmacológicas e não farmacológicas podem contribuir para aliviar os sintomas, retardar a progressão da doença e ...
Paulo Caramelli, Valeska Marinho, Jerson Laks, Marcus Vinicius Della Coletta, Florindo Stella, Einstein Francisco Camargos, Jerusa Smid, Breno José Alencar Pires Barbosa, Lucas Porcello Schilling, Marcio Luiz Figueredo Balthazar, Norberto Anízio Ferreira Frota, Leonardo Cruz de Souza, Francisco Assis Carvalho Vale, Márcia Lorena Fagundes Chaves, Sonia Maria Dozzi Brucki, Ricardo Nitrini, Helen Bedinoto Durgante, Paulo Henrique Ferreira Bertolucci   +17 more
doaj   +2 more sources