Results 131 to 140 of about 36,366 (264)

Translophagy—A potential link between autophagy impairment and translational errors

FEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk, Gailing Ma, Robin Antrobus, Diego Manni, Marco Trevisan‐Herraz, Mustafa Khwaja, Max Brown, Gavin D. Richardson, Masaaki Komatsu, Daniel Erskine, Viktor I. Korolchuk, Tetsushi Kataura   +11 more
wiley   +1 more source

Spatiotemporal transferability of multi-temporal random forest model for mapping <i>Euryale ferox</i> Salisb. plantations using Sentinel-2 imagery. [PDF]

Front Plant Sci
Zhang K, Wang S, Chen C, He X, Cai M, Li X, Long J, Wang X.   +7 more
europepmc   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

FEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell, Thomas Walther, Egbert Hoiczyk   +2 more
wiley   +1 more source

Vertical accuracy of ASTER, SRTM, and NASADEM digital surface models across Malawi's diverse topography. [PDF]

PLoS One
Nazombe KS, Chunga BA, Bakolo C, Mlewa R, Nhamo G.   +4 more
europepmc   +1 more source

Structural and biochemical analysis of a B12 superbinder

FEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices, Jacob J. Whittaker, Dirk J. Slotboom, Albert Guskov   +3 more
wiley   +1 more source

Transarterial Embolization Alone Versus Drug-Eluting Microspheres Chemoembolization for Hepatocellular Carcinoma (RAD-18-TAcE): A Multicenter Randomized Clinical Trial. [PDF]

Cardiovasc Intervent Radiol
Mosconi C, Taninokuchi Tomassoni M, Zanella S, Paccapelo A, Marasco G, Gusmini S, Ratti F, Palumbo D, Sironi S, Muglia R, Fronda MME, Calandri M, Fonio P, Marra P, Doriguzzi Breatta A, Cucchetti A, De Cobelli F, Renzulli M.   +17 more
europepmc   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

FEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav, Bogdan I. Florea, Sebastian Geibel   +2 more
wiley   +1 more source

Assessing the Applicability of Sentinel-1 D-InSAR for Snow Depth Retrieval in the Maxian Mountains. [PDF]

Sensors (Basel)
Feng T, Zhu J, Cai Z, He W.
europepmc   +1 more source

Granular Dynamics of the Mixing Processes for Different RPM Using DEM

, 2014
This paper emphasizes on the computer simulations of the granular materials via Discrete Element Method (DEM) by using open-source software LIGGGHTS. The examined process was mixing of two granular materials distinct by colour. The different initial conditions have led to finding the best way of homogenization, but it also shows the new perspective of ...
openaire   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

FEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source