Results 251 to 260 of about 166,782,770 (304)

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

[Validation of a new portable measurement method for home use-a feasibility study]. [PDF]

Urologie
Wirth U, Holze S, Wagner C, Bonaventura A, Siemer S.   +4 more
europepmc   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

Multi-scale ecosystem service dataset for Southern Hilly Region of China (1990-2024). [PDF]

Sci Data
Tang Z, Wu Y, Ding C, Song H, Qi L.
europepmc   +1 more source

Thalamic nuclei volumes across psychiatric and neurological disorders: a multi-site magnetic resonance imaging study. [PDF]

Transl Psychiatry
Mäki-Marttunen V, Nerland S, Jørgensen KN, Høgestøl EA, Rokicki J, Alnæs D, Borgwardt S, Boye B, Buitelaar J, Bøen E, Cervenka S, Conzelmann A, Erhardt S, Franke B, Celius EG, Harbo HF, Hilland E, Hoekstra P, Hartman CA, Jonassen R, Jönsson EG, Landrø NI, Lesch KP, Maglanoc LA, Pauli P, Sellgren CM, Nygaard GO, Oosterlaan J, Schmidt A, Schmidt A, Schwarz E, Ziegler GC, Agartz I, Westlye LT, Andreassen OA, Kaufmann T, Elvsåshagen T.   +36 more
europepmc   +1 more source

Elevation uncertainties in the Mekong Delta quantified using a transferable approach. [PDF]

Sci Rep
Seeger K, Minderhoud PSJ.
europepmc   +1 more source

Optimizing Stratification in Binary Colloidal Supraparticles. [PDF]

Adv Sci (Weinh)
Rudlof F, Wolf S, Schaller S, González JM, Schilde C, Vogel N.   +5 more
europepmc   +1 more source

Daily air temperature estimates at 30-meter resolution in the Chongqing Metropolitan Area, China, 2016-2024. [PDF]

Sci Data
Zhou W, Yang S, Zhu H, Liu Z, Zhao M, Zhou Y.   +5 more
europepmc   +1 more source

Cytokine release syndrome after allogeneic hematopoietic stem cell transplantation using posttransplant cyclophosphamide: current understanding and management. [PDF]

Front Immunol
Wang J, Arora K, de Lima M.
europepmc   +1 more source