Results 231 to 240 of about 168,301,947 (302)

Smaller is better: nanobodies meet NMR

FEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

Individual differences in prosocial learning are represented in the hippocampal dorsal CA1. [PDF]

Nat Neurosci
La Greca F, Zianni E, Cerchiaro I, Gusmini M, Coccia G, Carrea A, Pelucchi S, Castoldi C, Maggioni D, Marcello E, Silva BA, Gardoni F, DiLuca M, Scheggia D.   +13 more
europepmc   +1 more source

Invisible but not inaccessible—Revealing transient oligomers formed by intrinsically disordered proteins with solution NMR and complementary methods

FEBS Letters, EarlyView.
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley   +1 more source

Pitfalls and Inherent Biases in Liquid Handling Robotics: Investigations in Automation for SI Traceable Measurements. [PDF]

Anal Chem
Hambidge T, Corless S, Cowen S, Short M, Hopley C, Sears P.   +5 more
europepmc   +1 more source

Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research

FEBS Letters, EarlyView.
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley   +1 more source

Theory-based flood disaster education enhances disaster preparedness among adolescents in Selangor, Malaysia: a cluster randomized controlled study. [PDF]

Sci Rep
Makmon K, Azman AZF, Abdul Manaf R, Baharudin MR.   +3 more
europepmc   +1 more source

Inhibition of dipeptidyl peptidase 7 impairs lysophagy in LLOMe‐treated HepG2 cells

FEBS Letters, EarlyView.
DPP7 inhibition delays ubiquitin‐dependent lysophagy by attenuating ubiquitin accumulation and the recruitment of SQSTM1 and LC3 to damaged lysosomes, resulting in delayed clearance of damaged lysosomes and impaired restoration of lysosomal homeostasis. Created using FigureLabs (Certificate ID: FL‐PUB‐20260922‐Z99XNX).
Na Yeon Park, Inho Kwon, Yong Hwan Kim, Ji‐Eun Bae, Joon Bum Kim, Seong Hyun Kim, Sungho Maeng, Doo Sin Jo, Dong‐Hyung Cho   +8 more
wiley   +1 more source

Subglacial water flow and ice dynamics during glacial lake outburst floods observed from space. [PDF]

Nat Commun
Magnússon E, Drouin V, Pálsson F, Jóhannesson T, Belart JMC, Wuite J, Tolpekin V, Hannesdóttir K, Berthier E, Sigurðsson G, Einarsson B, Ófeigsson BG, Nagler T, Gudmundsson MT, Högnadóttir T.   +14 more
europepmc   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

Lightweight Multispectral Detection and DEM-Constrained Ray Consistency Localization for UAV-Assisted Search and Rescue. [PDF]

Sensors (Basel)
Bai Y, Zhu C.
europepmc   +1 more source