Results 201 to 210 of about 35,059 (266)

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Pupillometry and brain-wide c-Fos mapping uncover multimodal mirror emotional contagion related networks of mice. [PDF]

iScience
Caldarelli M, Zucca S, Viglione A, Stella A, Nisar R, Sagona G, Papini EM, Carrara F, Bovetti S, Mazziotti RM, Pizzorusso T.   +10 more
europepmc   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

FEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas, Brigitta Maruzs, Zsófia E. Kálmán, Tomas Klumpler, Gyula Batta, Bálint Péterfia, Zoltán Gáspári   +6 more
wiley   +1 more source

Consequences of iron exposure and glutathione depletion on redox balance, lipidome, and neurotransmission in C. elegans. [PDF]

Redox Biol
Gremme A, Gerisch E, Wieland D, Hillebrand J, Drews F, Pirritano M, Weishaupt AK, Fuss J, Schwantes V, Scholz J, Michaelis V, Thiel A, McColl G, Michalke B, Simon M, Hayen H, Bornhorst J.   +16 more
europepmc   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

FEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Vegetation dynamics inside Mediterranean vineyards: A dataset for tracking changes using unmanned aerial vehicles. [PDF]

Data Brief
Faucher M, Brunel G, Cheraiet A, Enard C, Feurer D, Vinatier F, Garcia L.   +6 more
europepmc   +1 more source

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

FEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson, Tomáš Gedeon, Mauricio Garcia Benitez, Campbell Putnam, William R. Harcombe, Radhakrishnan Mahadevan, Ashley E. Beck   +6 more
wiley   +1 more source

New inventory of glaciers in Tajikistan from 3 m PlanetScope imagery (2024): the Tajikistan Glacier Inventory (TGI). [PDF]

Sci Data
Li R, Li J, Gulayozov M, Safarov M, Halimov A.   +4 more
europepmc   +1 more source

HYDROLOGICAL SIMULATION FOR AN IMAGINARY FLOWPATH GENERATED FROM DIFFERENT DEM SOURCES

Proceeding of Annual Conference, 2005
KU, HyeJin, KAZAMA, So, SAWAMOTO, Masaki
openaire   +1 more source

Electron transfer between complexes III and IV in S. cerevisiae mitochondrial membranes

FEBS Letters, EarlyView.
Mitochondrial oxidative phosphorylation in S. cerevisiae mitoplasts is limited by complex IV catalytic capacity, rather than two‐dimensional cytochrome c diffusion. At physiological cytochrome c : supercomplex ratios at salinity equivalent to that of 20 mm monovalent salt, activity is maximized, indicating that this low ionic strength accurately mimics
Ana Paula Lobez, Mikael Oliveberg, Peter Brzezinski   +2 more
wiley   +1 more source