Results 221 to 230 of about 501,588 (251)

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

Neuropsychiatric symptoms and emerging dementia in people with Down syndrome and older adults. [PDF]

open access: yesAlzheimers Dement
Magana-Ramirez CM   +11 more
europepmc   +1 more source

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