Results 91 to 100 of about 35,022 (266)
Bangladesh has experienced multiple freshwater issues including salinization from monsoonal floods and groundwater over-pumping that induces severe land subsidence.
Kuo-Hsin Tseng +7 more
doaj +1 more source
The accurate estimation of terrain characteristics is central in rainfall runoff modelling. In this study, influences of Digital Elevation Models (DEMs) obtained from different sources, resolutions...
Ali H. Ahmed Suliman +3 more
openaire +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Diversity and complexity in neural organoids
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Study on DEM Correction Method of Digital Twin Basic Data Baseboard
DEM is one of the most important digital twin basic data and has played a huge role in water conservancy planning,design,and engineering construction.However,the existence of various DEM errors greatly reduces the credibility of analysis and application ...
HONG Minghai +8 more
doaj
A key aspect of geomorphological enquiry is concerned with quantitatively monitoring\ud the development of the Earth’s surface, in a diverse set of environments, and at a range of spatial\ud scales and temporal frequencies. A variety of geomatics technologies facilitate the acquisition of\ud multitemporal survey data that can be used to construct ...
openaire
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
The orthorectified Sentinel-2 images have systematic offset errors in areas with large surface elevation changes in the cases of open pit mining, land collapse and glacier movement, which can lead to the misinterpretation of geological features ...
Jianqi Lou +3 more
doaj +1 more source

