Results 191 to 200 of about 176,548,671 (230)

Fluxional Monomers Remodel Crystallinity at Low Loadings in Diketopyrrolopyrrole Co‐Thienothiophene Conjugated Polymers

open access: yesAngewandte Chemie, EarlyView.
Bullvalene is a fluxional molecule capable of adopting numerous conformations spontaneously; just like a Rubik's Cube. In this paper, we explore the incorporation of bullvalene into the backbone of a highly rigid conjugated polymer semiconductor and observe that the inherent fluxionality reduces average crystallite size.
Shine H. Huang   +7 more
wiley   +2 more sources

Integrating Genetic Modifier Genotype With Serum Proteomics in Duchenne Muscular Dystrophy Clinical Trials Links LTBP4 Genetic Modifier to IL‐23/CD93 Pathways in Muscle

open access: yesAmerican Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Genetic modifiers of Duchenne muscular dystrophy (DMD) that alter disease severity or response to therapy have been reported using natural history or registry data sets of older corticosteroid‐treated patients. We tested associations of genetic modifiers on motor function outcomes in young (4 to < 7 years) steroid naïve clinical trial ...
Utkarsh J. Dang   +16 more
wiley   +1 more source

Genetic Resilience and Resistance in Alzheimer's Disease Diagnosis and Pathology

open access: yesAnnals of Neurology, EarlyView.
Objective Some individuals avoid Alzheimer's disease (AD) pathology as they age, or retain cognition despite substantial pathology, suggesting mechanisms of resistance or resilience to neurodegeneration. Educational attainment (EA) is associated with reduced risk of cognitive decline, although the underlying mechanisms remain unclear.
Ganna Leonenko   +8 more
wiley   +1 more source

Demonstration of a Two‐Electron Pathway in Piezoelectric Mechanochemistry: Synthesis and Mechanical Adaptation of Polythiourethane

open access: yesAngewandte Chemie, EarlyView.
A mechano‐triggered polythiourethane (PTU) synthesis mediated by a two‐electron pathway. The polymerization proceeds efficiently (<1 h) under focused ultrasound, achieving >90% conversion without any conventional base catalyst. The approach demonstrates broad compatibility with various thiol/isocyanate monomer combinations, highlighting its synthetic ...
Yixiao Dong   +7 more
wiley   +2 more sources

Nonnative Thiol and Aniline Methylation, Including Enantioselective Dithiol Desymmetrization, by Multicomponent Cobamide‐Dependent Methyltransferases Using Unactivated Methyl Donors

open access: yesAngewandte Chemie, EarlyView.
Mixed MtaABC/MtgABC methyltransferase systems were developed for non‐native thiol and aniline methylation using the unactivated methyl donors methanol and glycine betaine. The platform enabled site‐selective and enantioselective methylation with turnover number up to 6000, representing the first enantioselective non‐native catalysis by cobamide ...
Amardeep Kumar   +3 more
wiley   +1 more source

Message-Passing Monte Carlo: Generating low-discrepancy point sets via graph neural networks. [PDF]

open access: yesProc Natl Acad Sci U S A
Rusch TK   +4 more
europepmc   +1 more source

Overview of Research Progress and Development of Cathode Materials for Aqueous Na‐Ion Batteries

open access: yesAsia-Pacific Journal of Chemical Engineering, EarlyView.
ABSTRACT Aqueous sodium‐ion batteries (ASIBs) have now been viewed as the promising energy storage technique for the grid application due to their intrinsic safety and cost‐effectiveness. However, their energy density and cycling stability are still unsatisfactory accompanied by the narrow electrochemical stability window of water and parasitic side ...
Zhiwei Shi   +5 more
wiley   +1 more source

Deciphering the Palimpsest: Chronological Uncertainty and the Interpretation of Mining Landscapes at Písečný vrch (Czech Republic)

open access: yesArchaeological Prospection, EarlyView.
ABSTRACT We investigated the Písečný vrch (Czech Republic), a site exploited for quartz mining in both prehistoric times and the 20th century. Due to their morphological similarity across all mining periods, the differentiation between pits with archaeological potential and recent ones is challenging.
Jan Fišer   +5 more
wiley   +1 more source

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