Results 51 to 60 of about 93,645 (262)

A Slack Departure Strategy for Demand Responsive Transit Based on Bounded Rationality

Journal of Advanced Transportation, 2022
Demand responsive transit (DRT) is emerging as one of the most potential travel modes to satisfy flexible travel demands. Nevertheless, how to attract more passengers has become a critical problem in the success of DRT projects.
Hongfei Wang, Hongzhi Guan, Huanmei Qin, Wanying Li, Junze Zhu   +4 more
doaj   +1 more source

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

FEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

Integrating Demand-Responsive Transportation into Smart City Strategies: Implications for Sustainable Urban Mobility in the European Union—A Systematic Literature Review and Survey Analysis

Logistics
Background: This study seeks to explore the link between smart city development and demand-responsive transport, analyze the ways of integrating demand-responsive transport into smart mobility concepts, estimate public perceptions about those phenomena ...
Patrik Eszes, László Buics
doaj   +1 more source

Electron transfer between complexes III and IV in S. cerevisiae mitochondrial membranes

FEBS Letters, EarlyView.
Mitochondrial oxidative phosphorylation in S. cerevisiae mitoplasts is limited by complex IV catalytic capacity, rather than two‐dimensional cytochrome c diffusion. At physiological cytochrome c : supercomplex ratios at salinity equivalent to that of 20 mm monovalent salt, activity is maximized, indicating that this low ionic strength accurately mimics
Ana Paula Lobez, Mikael Oliveberg, Peter Brzezinski   +2 more
wiley   +1 more source

Performance analysis and fleet requirements of automated demand-responsive transport systems as an urban public transport service

International Journal of Transportation Science and Technology, 2018
The introduction of public transport services by fully automated vehicles can potentially change the way public transit services will be operated, as they allow shifting from rigid scheduled and route-bound services towards flexible, demand-responsive ...
Konstanze Winter, Oded Cats, Gonçalo Correia, Bart van Arem   +3 more
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Quantifying Thermal Demand in Public Space: A Pedestrian-Weighted Model for Outdoor Thermal Comfort Design

Buildings
With accelerating urbanization, the outdoor thermal environment has become a critical factor affecting the thermal comfort of public spaces, particularly in high-density commercial districts and pedestrian-concentrated areas.
Deyin Zhang, Gang Liu, Kaifa Kang, Xin Chen, Shu Sun, Yongxin Xie, Borong Lin   +6 more
doaj   +1 more source

Stimuli-responsive chitosan-based nanocarriers for cancer therapy [PDF]

BioImpacts, 2017
Introduction: Stimuli-responsive nanocarriers offer unique advantages over the traditional drug delivery systems (DDSs) in terms of targeted drug delivery and on-demand release of cargo drug molecules.
Marziyeh Fathi, Parham Sahandi Zangabad, Sima Majidi, Jaleh Barar, Hamid Erfan-Niya, Yadollah Omidi   +5 more
doaj   +1 more source

Phosphoinositides and inositol phosphates as molecular glues

FEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry, Alexander J. Cutright, Mong Na Claire Loi, Jessica Martin, Joseph W. Gilligan, Jakub N. Kubina, Michael J. Arambula, Susanna Tanada Palmu, Daniella Zhou, Raymond D. Blind   +9 more
wiley   +1 more source

Vehicle scheduling optimization for demand responsive transit with flexible stops

Shenzhen Daxue xuebao. Ligong ban
Flexible stops demand responsive transit is a public transportation mode that combines fixed service stops with the ability for passengers to book at flexible stops.
SHEN Zikang, JIN Wenzhou, ZHENG Yajing
doaj   +1 more source